个人简介

Undergraduate Studies, University of Belgrade, 1999 Ph.D., Iowa State University, 2004 Postdoctoral Fellow, Yale University, 2006-2011 Assistant Professor of Chemistry, Virginia Tech, 2011-present

研究领域

Biomaterials/Chemical Biology/Bioanalytical

Many fundamental, yet complex, biological functions are carried out by molecular machineries composed of biopolymers, especially proteins and peptides. Recent advancements in protein and peptide engineering tools have facilitated scientific progress towards a new class of soft materials that merge unique properties of bio- and synthetic polymers. The Grove lab focuses on design and synthesis of proteins and peptides for a broad variety of applications including assembly of nanostructured materials with tunable morphology and function, biosensing, and drug delivery. Our work is highly interdisciplinary and students will receive training in several areas of chemistry, structural biology, and materials science. Current projects include: Synthesis, assembly, and characterization of protein-polymer conjugates Biotemplating of inorganic nanoparticles for optical sensors Design of capture agents for glycan sensing Design of theranostic nanoparticles

近期论文

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Tijana Z. Grove, Chinedum O. Osuji, Jason D. Forster, Eric R. Dufresne, Lynne Regan; "Stimuli-Responsive Smart Gels Realized via Modular Protein Design" J. Am. Chem. Soc. 2010, 132, 14024-14026. Tijana Z. Grove, Michael Hands, Lynne Regan; "Creating novel proteins by combining design and selection" Protein Eng. Des. Sel. 2010, 23, 449-55. Tijana Z. Grove, Aitziber L. Cortajarena, Lynne Regan; "Ligand binding by repeat proteins: natural and designed" Curr. Opin. Struct. Biol. 2008, 18, 507-15.