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刘家国,南京农业大学优秀青年骨干教师;中国兽药典委员会中药专业委员会委员;中国畜牧兽医学会中兽医学分会理事,华东区中兽医研究会副理事长,江苏省中西兽医结合研究会副理事长。1994 年 6 月四川 畜牧兽医学院兽医本科专业毕业,获学士学位;1997 年 6 月南京农业大学中兽医病理专业硕士研究生毕业,获硕士学位;2005 年 12 月南京农业大学临床兽医学博士研究生毕业,获博士学位。自 1994 年以来,一直从事中兽医学的教学和科研工作。主讲本科生、研究生课程多门,指导博、硕士研究生 30 余名;主持国家自然科学基金面上项目 2 项,国家公益性行业专项子专题 3 项,江苏省自然科学基金和其他部省级及横向合作课题 10 余项。主、参编教材、专著 30 余部,作为副主译翻译的“中英对照《元亨疗马集许序注释》”及“中英对照《元亨疗马集选释》(牛、驼经)”已在海内外公开出版发行,发表论文 100 余篇,其中 SCI 收录 40 余篇;参与研制成功 6 项新中兽药,获 2 项国家新兽药证书;获省级科研奖 1 项、国家发明专利 10 余项;曾被评为优秀共产党员,全国中兽医工作精英等。培训来自德国、英国、希腊、土耳其、日本、韩国等的国际兽医针灸留学生 400 余名。 科研项目: 1. 几种中药多糖和黄酮成分与其衍生物抗鸭病毒性肝炎作用机制的比较研究-国家自然科学基金 主持 2. 磷酸化分子修饰提高中药甙糖类成分抗病毒活性及其机理研究-国家自然科学基金 主持 3. 新中兽药"芪蓝饮"防治鸡传染性法氏囊病的神经内分泌免疫机制研究江苏省自然科学基金 主持 4. 公益性行业(农业)科研重大专项经费-中兽药生产关键技术研究与应用-抗鸭病毒性肝炎中兽药有效成分(部位)复方制剂生产关键技术研究与应用 主持 5. 高效绿色饲料(中药)配制关键技术-上海市科委 主持 荣誉奖项: 南京农业大学优秀骨干教师 我国几种危害严重的群发性畜禽营养代谢病的防控研究 神农中华农业科技奖 第三 发明专利: [1] 刘家国,熊文,陈云,曾玲,武毅,王德云,胡元亮,马秀丽,黄兵,兰邹然.一种中药淫羊藿总黄酮磷酸化分子修饰方法.专利号:ZL201310147904.2. [2] 刘家国,陈云,熊文,曾玲,徐美云,王德云,胡元亮,武毅,黄兵,马秀丽.一种抗鸭病毒性肝炎山豆根多糖及其分子修饰物.专利号:ZL201410009323.7. [3] 刘家国、曾玲、徐美云、宋美芸、陈云、熊文、王德云、胡元亮、武毅、黄兵. 一种抗鸭病毒性肝炎中药提取物复方. 专利号:ZL201410103689.0

研究领域

中兽医学与中兽药学

近期论文

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1. Liu Jiaguo,Wu Hongxing,Wang Deyun,Zhang Fan,Song Dalu. Treatment of equine intestinal constipation with integrated traditional Chinese and Western veterinary medicine. Equine Veterinary Education, 2014, 26(12), 632-634 2. Jia-Guo Liu, Hong-Jin Zhao, Yan-Juan Liu, Yong-wang Liu, Xiao-Long Wang. Effect of two selenium sources on hepatocarcinogenesis and several angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. Journal of Trace Elements in Medicine and Biology. 2012 ,(26):255– 261 3. Jia-Guo Liu, Hong-Jin Zhao, Yan-Juan Liu, Xiao-Long Wang. Effect of selenium-enriched malt on VEGF and several relevant angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. Journal of trace element in medicine and biology.2010,24:52–57 4. Jia-Guo Liu, Hong-Jin Zhao, Yan-Juan Liu, Xiao-Long Wang. Effect of selenium-enriched malt on hypoglycemia and regulatory hormones in diethylnitrosamine-induced hepatocarcinoma SD rats. Research in Veterinary Science,2009,87 (3): 438–444 5. Jia-Guo Liu, Hong-Jin Zhao, Yan-Juan Liu, Xiao-Long Wang. Effect of selenium-enriched malt on hepatocarcinogenesis, paraneoplastic syndrome and the hormones regulating blood glucose in rats treated by diethylnitrosamine. Life Sciences,2006,78(20):2315-2321. 6. Jia-Guo Liu,Cui-Ling Pan,Yong-Wang Liu,Wei-dong Sun,Hong-jin Zhao, Yan-juan Liu,Cheng-hua He,Xiao-long Wang. The intravenous glucose tolerance test in Water Buffalo. Research in Veterinary Science,2004,77(1):23-27. 7. Jiaguo Liu, Ke Ming, Yuanliang Hu, Baokang Zhang, Dalu Song. Effect of Epimedium-propolis adjuvant on the nonspecific immunologic functions of experimental animals. The American Journal of Traditional Chinese Veterinary Medicine, 2016,11(1):29-34. 8. Yun Chen, Ling Zeng, Yu Lu, Yulan Yang, Meiyun Xu, Yixuan Wang, Jiaguo Liu*. Treatment effect of a flavonoid prescription on duck virus hepatitis by its hepatoprotective and antioxidative ability. Pharmaceutical Biology , 2017,55(1):198-205 9. Yun Chen, Fangke Yao, Ke Ming, Deyun Wang, Yuanliang Hu, Jiaguo Liu *.Polysaccharides from traditional Chinese medicine: Extraction, Purification, Modification and Biological activity. Molecules, 2016, 21(12), 1705. 10. Yixuan Wang, Yun Chen, Hongxu Du, Jingjing Yang, Ke Ming, Meiyun Song and Jiaguo Liu*. Comparison of the anti-duck hepatitis A virus activities of phosphorylated and sulfated Astragalus polysaccharides. Experimental Biology and Medicine,2016; 0: 1–10 11. Ke Ming, Yun Chen, Fangke Yao, Jintong Shi, Jingjing Yang, Hongxu Du, Xunyi Wang, Yixuan Wang, Jiaguo Liu, *. Phosphorylated Codonopsis pilosula polysaccharide could inhibit the virulence of duck hepatitis A virus compared with Codonopsis pilosula polysaccharide. International Journal of Biological Macromolecules,2017(94),28-35. 12. Fangke Yao, Yun Chen, Jintong Shi, Ke Ming, Jiaguo Liu*, Wen Xiong, Meiyun Song, Hongxu Du, Yixuan Wang, Shuaibin Zhang, Yi Wu, Deyun Wang, Yuanliang Hu. Replication cycle of duck hepatitis A virus type 1 in duck embryonic hepatocytes. VIROLOGY,2016,491:73-78 13. Hongxu Du, Shuaibing Zhang, Meiyun Song, Yixuan Wang, Ling Zeng, Yun Chen, Wen Xiong, Jingjing Yang, Fangke Yao, Yi Wu, Deyun Wang, Yuanliang Hu, Jiaguo Liu*. Assessment of a flavone-polysaccharide based prescription for treating duck virus hepatitis.PLOS ONE,2016,1:1-16 14. Yun Chen, Ling Zeng, Wen Xiong, Meiyun Song, Hongxu Du, Yixuan Wang, Ke Ming, Yi Wu, Deyun Wang, Yuanliang Hu, Jiaguo Liu*. Anti- duck virus hepatitis mechanisms of Bush Sophora Root polysaccharide and its sulfate verified by intervention experiments. Virus research,2015(204)):58-67 15. Yun Chen, Yi Wu, Luanting Xian, Meiyun Song, Ling Zeng, Wen Xiong, Jiaguo Liu*, Weidong Sun*, Deyun Wang, Yuanliang Hu. Effects of Bush Sophora Root polysaccharide and its sulfate on immuno-enhancing of the therapeutic DVH. International Journal of Biological Macromolecules, 2015,(80):217-224. 16. Wen Xiong, Xia Ma,Yi Wu,Yun Chen,Ling Zeng,Jiaguo Liu*, Weidong Sun*, Deyun Wang,Yuanliang Hu. Determine the structure of phosphorylated modification of icariin and its antiviral activity against duck hepatitis virus A. BMC Veterinary Research,2015(11):205-213 17. Yun Chen, Meiyun Song, Yixuan Wang, Wen Xiong, Ling Zeng, Shuaibing Zhang, Meiyun Xu, Hongxu Du, Jiaguo Liu*, Deyun Wang, Yi Wu, Yuanliang Hu. The anti-DHAV activities of Astragalus polysaccharide and its sulfate compared with those of BSRPS and its sulfate. Carbohydrate Polymers, 2015,(117):339–345 18. Wen Xiong,Yun Chen,Yu Wang,Jiaguo Liu*. Roles of the antioxidant properties of icariin and its phosphorylated derivative in the protection against duck virus hepatitis. BMC Veterinary Research,2014(10):226-235 19. Yun Chen, Wen Xiong, Ling Zeng, Yu Wang, Shuaibing Zhang, Meiyun Xu, Meiyun Song, Yixuan Wang, Hongxu Du, Jiaguo Liu*, Deyun Wang, Yi Wu, Yuanliang Hu. Bush Sophora Root polysaccharide and its sulfate can scavenge free radicals resulted from duck virus hepatitis. International Journal of Biological Macromolecules,2014,(66):186-193 20. Yun Chen, Wen Xiong, Ling Zeng, Deyun Wang, Jiaguo Liu*, Yi Wu, Yuanliang Hu. Comparison of Bush Sophora Root polysaccharide and its sulfate’s anti-duck hepatitis A virus activity and mechanism. Carbohydrate Polymers. 2014 (102): 333–340 21. Zhang Yuqing†, Sun Zhan’ao†, Liu Jiaguo*, Wang Deyun*, Zhang Baokang, Yi Fang, Fan Yunpeng, Liu Dan, Liu Xu, Liu Cui, Hu Yuanliang. Flavone ingredients can synergistically inhibit NDV infecting cell and improve ND vaccine’s protective rate. International Journal of Biological Macromolecules, 2012,51: 201– 208 主要论著 1. 刘家国,武彩红(主编).土法良方治猪病.化工出版社,2010.5 2. 刘家国(主编).土法良方治猪病(二版).化工出版社,2016.1 3. 刘家国.王德云(主编).新编猪场疾病控制技术.化工出版社,2009.1 4. 宋大鲁,宋旭东,刘家国(副主编),等.宠物急诊救治手册.中国农业出版社,2007.7 5. 宋大鲁,宋旭东,刘家国(副主编),等.宠物诊疗金鉴.中国农业出版社,2009.1 6. 孙卫东,刘家国(主编),等.经济动物疾病诊疗与处方手册.化工出版社,2008.1 7. 胡元亮,刘家国(参编),等.兽医中药学(全国高等农林院校“十一五”规划教材).中国农业出版社,2007.6 8. 宋大鲁,宋旭东,刘家国(参编),等.犬猫针灸疗法. 中国农业出版社,2009.6 9. 孙卫东,刘家国(副主编),等.全国执业兽医资格考试综合模拟题及考前冲刺.化工出版社,2011.5 10. 孙卫东,刘家国(副主编),等.全国执业兽医资格考试综合模拟题及考前冲刺.化工出版社,2012.5 11. 宋大鲁,刘家国(副主译).中英对照《元亨疗马集许序注释》.中国农业出版社,2012.8 12. 许剑琴,刘家国(参编),等.中兽医学精编版(普通高等教育农业部“十二五”规划教材,全国高等农林院校“十二五”规划教材),中国农业出版社,2014.1 13. 宋大鲁,刘家国(副主译). 中英对照《元亨疗马集选释》(牛、驼经).中国农业出版社,2015.5 14. 宋大鲁,宋旭东,刘家国(副主编),等.宠物诊疗金鉴(二版).中国农业出版社,2016.3

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