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论文：
1. Chen C, Tian D, Su J, Liu X, Shah MAA, Li X, Xu L, Yan R, Song X *. Protective efficacy of
rhomboid-like protein 3 as a candidate antigen against Eimeria maxima in chickens. Front.
Microbiol. 2021, 12: 614229.
2. Chen Y, Tian D, Xu L, Yan R, Li X, Shah MAA, Song X*. Rhomboid protein 2 of Eimeria
maxima provided partial protection against infection by homologous species. Vet Res. 2021
Feb 18;52(1):29. doi: 10.1186/s13567-020-00886-7.
3. Li W, Wang M, Chen Y, Chen C, Liu X, Sun X, Jing C, Xu L, Yan R, Li X, Song X*. EtMIC3
and its receptors BAG1 and ENDOUL are essential for site-specific invasion of Eimeria
tenella in chickens. Vet Res. 2020 Jul 16;51(1):90.
4. 靖传旭，杨新朝，徐立新，严若峰，李祥瑞，宋小凯*．巨型艾美耳球虫偏菱形样蛋白
EmＲP 免疫原性分析. 畜牧与兽医，2020，52 ( 4) : 122-126．
5. Liu J, Liu L, Li L, Tian D, Li W, Xu L, Yan R, Li X, Song X*. Protective immunity induced
by Eimeria common antigen 14-3-3 against Eimeria tenella, Eimeria acervulina and Eimeria
maxima. BMC Vet Res. 2018 Nov 12;14(1):337.
6. 刘剑华，刘连瑞，李灵娟，徐立新，严若峰，李祥瑞，宋小凯*. 鸡球虫共同抗原 UCE
免疫原性分析及其对多种球虫感染的免疫保护效果评估. 南京农业大学学报 2018，
41(3): 496-503.
7. Tian L, Li W, Huang X, Tian D, Liu J, Yang X, Liu L, Yan R, Xu L, Li X, Song X*. Protective
Efficacy of Coccidial Common Antigen Glyceraldehyde 3-Phosphate Dehydrogenase
(GAPDH) against Challenge with Three Eimeria Species. Front Microbiol. 2017, 8: 1245.
8. Liu L, Huang X, Liu J, Li W, Ji Y, Tian D, Tian L, Yang X, Xu L, Yan R, Li X, Song X*.
Identification of common immunodominant antigens of Eimeria tenella, Eimeria acervulina
and Eimeria maxima by immunoproteomic analysis. Oncotarget. 2017, 8(21): 34935-34945.
9. Yang X, Li M, Liu J, Ji Y, Li X, Xu L, Yan R, Song X*. Identification of immune protective
genes of Eimeria maxima through cDNA expression library screening.Parasites & Vectors
2017, 10(1):85.
10. Song X, Zhao X, Xu L, Yan R, Li X. Immune protection duration and efficacy stability of
DNA vaccine encoding Eimeria tenella TA4 and chicken IL-2 against coccidiosis. Res Vet Sci.
2017, 111:31-35.
11. Song X, Zhang Z, Liu C, Xu L, Yan R, Li X. Evaluation of the persistence, integration,
histopathology and environmental release of DNA vaccine encoding Eimeria tenella TA4 and
chicken IL-2. Vet Parasitol. 2016, 229: 22-30.
12. Song X, Gao Y, Xu L, Yan R, Li X. Partial protection against four species of chicken coccidia
induced by multivalent subunit vaccine. Vet Parasitol. 2015 212(3-4):80-85.
13. Song X, Zhang R, Xu L, Yan R, Li X. Chimeric DNA vaccines encoding Eimeria acervulina
macrophage migration inhibitory factor (E.MIF) induce partial protection against
experimental Eimeria infection. Acta Parasitol. 2015 60(3):500-8.
14. Song X, Xu L, Yan R, Huang X, Li X. Construction of Eimeria tenella multi-epitope DNA
vaccines and their protective efficacies against experimental infection. Vet Immunol
Immunopathol. 2015 166(3-4):79-87.
15. Song X, Huang X, Yan R, Xu L, Li X. Efficacy of chimeric DNA vaccines encoding Eimeria
tenella 5401 and chicken IFN-γ or IL-2 against coccidiosis in chickens. Exp Parasitol. 2015
156:19-25.
16. Song X, Ren Z, Yan R, Xu L, Li X. Induction of protective immunity against Eimeria tenella,
Eimeria necatrix, Eimeria maxima and Eimeria acervulina infections using multivalent
epitope DNA vaccines. Vaccine. 2015 33(24):2764-70.
17. 李梦辉，刘连瑞，涂浩，黄经纬，张振超，徐立新，严若峰，李祥瑞，宋小凯*
.利用 gateway
技术构建巨型艾美耳球虫孢子化卵囊 cDNA 表达文库. 南京农业大学学报 2015,38（4）：
630-635.
18. 朱艳，滕佩，魏德康，张振超，徐立新，严若峰，李祥瑞，宋小凯*
. 柔嫩艾美耳球虫江
苏株微线蛋白-3 基因的克隆与序列分析. 畜牧与兽医 2014， 46（8）：75-79.
19. Xiaokai Song, Lixin Xu, Ruofeng Yan, Xinmei Huang, Mohammed Ali A. Shah, Xiangrui
Li*. The optimal immunization procedure of DNA vaccine pcDNA-TA4-IL-2 of Eimeria
tenella, its cross immunity to Eimeria necatrix and Eimeria acervulina. Veterinary
parasitology (IF: 2.579), 2009，159(1)：30-36.
20. Qianming Xu, Xiaokai Song(并列第一作者), Lixin Xu, Ruofeng Yan, Mohammed Ali A.
Shah, Xiangrui Li.Vaccination of chickens with a chimeric DNA vaccine encoding Eimeria
tenella TA4 and chicken IL-2 induces protective immunity against coccidiosis. Veterinary
Parasitology (IF: 2.579),2008,156(3-4): 319-323.
21. Sun W, Song X, Yan R, Xu L, Li X. Vaccination of goats with a glutathione peroxidase DNA
vaccine induced partial protection against Haemonchus contortus infection. Vet Parasitol 2011,
182(2-4): 239-247.
22. Muhammad Ali A. Shah, Xiaokai Song, Lixin Xu, Ruofeng Yan, Xiangrui Li*, Construction
of DNA vaccines encoding Eimeria acervulina cSZ-2 with chicken IL-2 and IFN-c and their
efficacy against poultry coccidiosis. Research in Veterinary Science, 2011, 90: 72–77
23. Wei Sun, Xiaokai Song, Ruofeng Yan, Lixin Xu, Xiangrui Li. Cloning and characterization of
a selenium-independent glutathione peroxidase (HC29) from adult Haemonchus contortus. J
Vet Sci, 2012, 13(1), 49-58.
24. Tang F, Xu L, Yan R, Song X and Li X. Evaluation of the immune response induced by DNA
vaccines expressing MIF and MCD1genes of Trichinella spiralis in BALB/c mice. J
Helminthol. 2012, 86:430–439
25. Kaikai Han, Lixin Xu, Ruofeng Yan, Xiaokai Song, Xiangrui Li*. Molecular cloning,
expression and characterization of enolase from adult Haemonchus contortus. Research in
Veterinary Science, 2012, 92: 259–265
26. GuangWei Zhao, Bo Shen, Qing Xie, Li Xin Xu, Ruo Feng Yan, Xiao Kai Song, I.A. Hassan,
Xiang Rui Li∗. Detection of Toxoplasma gondii in free-range chickens in China based on
circulating antigens and antibodies. Veterinary Parasitology, 2012, 18, 572–577
Han K, Xu L, Yan R, Song X, Li X*. Cloning, expression and characterization of
NAD1-dependent glyceraldehyde-3-phosphate dehydrogenase of adult Haemonchus contortus.
Journal of Helminthology, 2011, 85: 421–429
27. Han K, Xu L, Yan R, Song X, Li X. Vaccination of goats with glyceraldehyde-3-phosphate
dehydrogenase DNA vaccine induced partial protection against Haemonchus contortus. Vet
Immunol Immunopathol. 2012, 149: 177-185
28. Zhao G, Shen B, Xie Q, Xu L, Yan R, Song X, Hassan Ibrahim Adam and Li X. Isolation and
Molecular Characterization of Toxoplasma gondii from Chickens in China. Journal of
Integrative Agriculture, 2012, 11(8): 1347-1353
29. Huili Zhu, Ruofeng Yan, Song Wang, Xiaokai Song, Lixin Xu, Xiangrui Li. Identification
and molecular characterization of a novel antigen of Eimeria acervulina. Molecular and
Biochemical Parasitology, 2012, 186: 21-28
30. Zhu H, Xu L, Yan R, Song X, Tang F, Wang S, Li X. Identification and characterization of a
cDNA clone-encoding antigen of Eimeria acervulina. Parasitology, 2012, 139: 1711–1719.
31. Tang F, Xu L, Yan R, Song X, Li X. A DNA vaccine co-expressing Trichinella spiralis MIF
and MCD-1 with murine ubiquitin induces partial protective immunity in mice. J Helminthol.
2013, 87:24-33
32. Hongyan Song, Baofeng Qiu, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li . The
protective efficacy of chimeric SO7/IL-2 DNA vaccine against coccidiosis in chickens.
Research in Veterinary Science. 2013, 94: 562–567.
33. Ruofeng Yan, Wei Sun, Xiaokai Song, Lixin Xu, Xiangrui Li.Vaccination of goats with DNA
vaccine encoding Dim-1 induced partial protection against Haemonchus contortus: A
preliminary experimental study. Res. Vet. Sci. 2013, 95:189–199.
34. Ruofeng Yan, Lixin Xu, Jingjing Wang, Xiaokai Song, Xiangrui Li. Cloning and
characterization of aldolase from parasitic nematode Haemonchus contortus. Journal of
Animal and Veterinary Advances, 2013,12(4):478-486.
35. Meng Zhang, Zhen Yang, Shuai Wang, LongFei Tao, LiXin Xu, RuoFeng Yan, XiaoKai Song,
XiangRui Li. Detection of Toxoplasma gondii in shellfish and fish in parts of China.
Veterinary Parasitology, 2014, 200, 1-2: 85-89.
36. Shuai Wang, GuangWei Zhao, Wang Wang, Qing Xie, Meng Zhang, Cheng Yuan, Ibrahim
Adam Hassan, XinChao Liu, LiXin Xu, RuoFeng Yan, XiaoKai Song, and XiangRui Li.
Pathogenicity of two Toxoplasma gondii strains in chickens of different ages infected via
intraperitoneal injection. Avian Pathology, 2014, 43, 1: 1–5.
37. Wang Wang, Cheng Yuan, Shuai Wang, XiaoKai Song, LiXin Xu, RuoFeng Yan, I.A. Hasson,
XiangRui Li. Transcriptional and proteomic analysis reveal recombinant galectins of
Haemonchus contortus down-regulated functions of goat PBMC and modulation of several
signaling cascades in vitro. Journal of Proteomics, 2014, 98, 26:123–137.
38. Tran Duc Hoan, Doan Thi Thao , Javaid Ali Gadahi, Xiaokai Song, Lixin Xu, Ruofeng Yan,
Xiangrui Li. Analysis of humoral immune response and cytokines in chickens vaccinated with
Eimeria brunetti apical membrane antigen-1(EbAMA1) DNA vaccine. Experimental
Parasitology. 2014,144: 65–72.
39. Wang Wang, Shuai Wang, Hui Zhang, Cheng Yuan, RuoFeng Yan, XiaoKai Song, LiXin Xu
and XiangRui Li. Galectin Hco-gal-m from Haemonchus contortus modulates goat monocytes
and T cell function in different patterns. Parasites & Vectors 2014, 7:342.
40. Ruofeng Yan, Jingjing Wang, Lixin Xu, Xiaokai Song and Xiangrui Li*. DNA vaccine
encoding Haemonchus contortus Actin induces partial protection in Goats. Acta Parasitologica,
2014, 59(4), 698–709.
41. Ibrahim A Hassan, Shuai Wang, LiXin Xu, RuoFeng Yan, XiaoKai Song and Xiangrui Li.
DNA vaccination with a gene encoding Toxoplasma gondii Deoxyribose Phosphate Aldolase
(TgDPA) induces partial protective immunity against lethal challenge in mice. Parasites &
Vectors 2014, 7:431
42. Ibrahim A. Hassan, Shuai Wang, LiXin Xu, RuoFeng Yan, XiaoKai Song, XiangRui Li.
Immunoglobulin and cytokine changes induced following immunization with a DNA vaccine
encoding Toxoplasma gondii selenium-dependent glutathione reductase protein. Experimental
Parasitology, 2014, 146: 1–10
43. Hassan A, Wang S, Xu L, Yan R, Song X, Li X*. Immunological response and protection of
mice immunized with plasmid encoding Toxoplasma gondii glycolytic enzyme malate
dehydrogenase. Parasite Immunology, 2014, 36, 674–683
44. ZhenChao Zhang, JingWei Huang, MengHui Li, YuXia Sui, Shuai Wang, LianRui Liu, LiXin
Xu, RuoFeng Yan, XiaoKai Song, XiangRui Li*. Identification and molecular
characterization of microneme 5 of Eimeria acervulina. PLoS One. 2014, 9(12):e115411.
45. Shuai Wang, Ibrahim A. Hassan1, XinChao Liu, LiXin Xu, RuoFeng Yan, XiaoKai Song,
XiangRui Li. Immunological changes induced by Toxoplasma gondii
Glutathione-S-Transferase (TgGST) delivered as a DNA vaccine. Research in Veterinary
Science, 2015, 99, 157–164
46. Cheng Yuan, Hui Zhang, Wang Wang, Yan Li, RuoFeng Yan, LiXin Xu, XiaoKai Song and
XiangRui Li*.Transmembrane protein 63A is a partner protein of Haemonchus contortus
galectin in the regulation of goat peripheral blood mononuclear cells. Parasites & Vectors
2015, 8:211
47. Zhao Guangwei, Wang Shuai, Wang Wang, Zhang Zhenchao, Xie Qing, Zhang Meng, I A
Hassan, Yan Ruofeng, Song Xiaokai, Xu Lixin, Li Xiangrui. Type I strain of Toxoplasma
gondii from chicken induced different immune responses with that from human, cat and swine
in chicken. Journal of Integrative Agriculture 2015, 14(5): 956–965
48. Wang S, Zhang M, Liu, Lin T, Yang H, Yuan S, Zhao G, HASSAN IA, Yan R, Song X, Xu L,
Li X. Investigation on the co-infections of Toxoplasma gondii with PRRSV, CSFV or PCV-2
in swine in part of China. Journal of Integrative Agriculture, 2015, 14(9): 1838–1844
49. Huang Jingwei, Zhenchao Zhang, Menghui Li, Xiaokai Song, Ruofeng Yan, Lixin Xu,
Xiangrui Li. Eimeria maxima microneme protein 2 delivered as DNA vaccine and
recombinant protein induces immunity against experimental homogenous challenge.
Parasitology International, 2015, 64: 408–416
50. Jingwei Huang, Zhenchao Zhang, Menghui Li, Xiaokai Song, Ruofeng Yan, Lixin Xu &
Xiangrui Li. Immune protection of Microneme 7 (EmMIC7) against Eimeria maxima
challenge in chickens. Avian Pathology, 2015, 44, (5): 392–400
51. Shuai Wang, Yujian Wang, Xiaoni Sun, Zhenchao Zhang, Tingqi Liu, Javaid Ali Gadahi, Lixin
Xu, Ruofeng Yan, Xiaokai Song, Xiangrui Li. Protective immunity against acute
toxoplasmosis in BALB/c mice induced by a DNA vaccine encoding Toxoplasma gondii 10
kDa excretory–secretory antigen (TgESA10). Veterinary Parasitology, 2015, 214: 40–48
52. Shuai Wang, YuJian Wang, XiaoNi Sun, ZhenChao Zhang, TingQi Liu, Javaid Ali Gadahi,
Ibrahim Adam Hassan, LiXin Xu, RuoFeng Yan, XiaoKai Song and XiangRui Li. Protective
immunity against acute toxoplasmosis in BALB/c mice induced by a DNA vaccine encoding
Toxoplasma gondii elongation factor 1-alpha. BMC Infectious Diseases (2015) 15:448
53. Shuai Wang, Guang-Wei Zhao, Wang Wang, Zhen-Chao Zhang, Bo Shen, I. A. Hassan, Qing
Xie, Ruo-Feng Yan, Xiao-Kai Song, Li-Xin Xu, Xiang-Rui Li* Pathogenicity of Five Strains
of Toxoplasma gondii from Different Animals to Chickens. Korean J Parasitol, 2015, 53(2):
155-162
54. ZhenChao Zhang, Shuai Wang, JingWei Huang, LianRui Liu, MingMin Lu, MengHui Li,
YuXia Sui, LiXin Xu, RuoFeng Yan, XiaoKai Song, XiangRui Li. ∗Proteomic analysis of
Eimeria acervulina sporozoite proteins interaction with duodenal epithelial cells by shotgun
LC–MS/MS. Molecular & Biochemical Parasitology, 2015, 202: 29–33
55. Ulrich-Lynge SL, Dalgaard TS, Norup LR, Song X, Sørensen P, Juul-Madsen HR. Chicken
mannose-binding lectin function in relation to antibacterial activity towards Salmonella
enterica. Immunobiology. 2015, 220(5):555-563
56. ZhenChao Zhang, LianRui Liu, JingWei Huang, Shuai Wang, MingMin Lu, XiaoKai Song,
LiXin Xu, RuoFeng Yan, XiangRui Li*. The molecular characterization and immune
protection of microneme 2 of Eimeria acervulina. Veterinary Parasitology, 2016, 215: 96–105
57. Tran Duc Hoan, Zhenchao Zhang, Jingwei Huang, Ruofeng Yan, Xiaokai Song, Lixin Xu,
Xiangrui Li*. Identification and immunogenicity of microneme protein 2 (EbMIC2) of
Eimeria brunetti. Experimental Parasitology, 2016, 162: 7–17.
58. Wang F, Xu L, Song X, Li X, Yan R. Identification of differentially expressed proteins
between free-living and activated third-stage larvae of Haemonchus contortus. Vet Parasitol.,
2016, 215:72-77.
59. Zhang Z, Liu X, Yang X, Liu L, Wang S, Lu M, Ehsan M, Gadahi JA, Song X, Xu L, Yan R,
Li X. The Molecular Characterization and Immunity Identification of Microneme 3 of Eimeria
acervulina. J Eukaryot Microbiol., 2016, 63(6):709-721.
60. Gadahi JA, Yongqian B, Ehsan M, Zhang ZC, Wang S, Yan RF, Song XK, Xu LX, Li XR.
Haemonchus contortus excretory and secretory proteins (HcESPs) suppress functions of goat
PBMCs in vitro. Oncotarget. 2016, 7(24):35670-35679.
61. Gadahi JA, Li B, Ehsan M, Wang S, Zhang Z, Wang Y, Hasan MW, Yan R, Song X, Xu L, Li
X. Recombinant Haemonchus contortus 24 kDa excretory/secretory protein (rHcES-24)
modulate the immune functions of goat PBMCs in vitro. Oncotarget. 2016,
7(51):83926-83937.
62. Gadahi JA, Wang S, Bo G, Ehsan M, Yan R, Song X, Xu L, Li X. Proteomic Analysis of the
Excretory and Secretory Proteins of Haemonchus contortus (HcESP) Binding to Goat PBMCs
In Vivo Revealed Stage-Specific Binding Profiles. PLoS One 2016,11(7):e0159796.
63. Li Y, Yuan C, Wang L, Lu M, Wang Y, Wen Y, Yan R, Xu L, Song X, Li X. Transmembrane
protein 147 (TMEM147): another partner protein of Haemonchus contortus galectin on the
goat peripheral blood mononuclear cells (PBMC). Parasit Vectors 2016, 9(1): 355.
64. Wang S, Zhang Z, Wang Y, Gadahi JA, Xu L, Yan R, Song X, Li X. Toxoplasma gondii
Elongation Factor 1-Alpha (TgEF-1α) Is a Novel Vaccine Candidate Antigen against
Toxoplasmosis. Front Microbiol. 2017, 8:168.
65. 严若峰,宋小凯,徐立新,李祥瑞. 基于 ITS 序列的捻转血矛线虫系统进化分析. 畜牧兽医
学报,2012, 43(7):1117-1122
66. 严若峰,闫峰宾,王晶晶,徐立新,宋小凯,李祥瑞.捻转血矛线虫肌动蛋白基因的克隆与表达
及其 DNA 疫苗的构建.南京农业大学学报，2012,35(4):87-93
67. 董文阳,蒋静雅,陆浩,宋小凯,徐立新,严若峰,李祥瑞.南京地区流浪犬钩虫感染情况调查.
畜牧与兽医,2012,44(5):77-79
68. 张晓燕，严若峰，徐立新，宋小凯，李祥瑞.山羊白细胞介素-４成熟蛋白基因的原核表
达及其生物学活性检测. 畜牧兽医学报,2012,43(10):1675-1663
69. 张志凯, 徐立新, 宋小凯, 李祥瑞, 严若峰. 捻转血矛线虫新基因 Hcher-1 的克隆与特性
分析. 南京农业大学学报, 2012,35(6):89-96
70. 牛延萍, 高丽丽, 宋小凯, 徐立新, 李祥瑞, 严若峰. 捻转血矛线虫 ES24 抗原基因的克
隆与表达特性分析. 畜牧与兽医，2012,44（11）:17-20
71. 高波，袁橙，宋小凯，徐立新，严若峰，李祥瑞。捻转血矛线虫谷胱甘肽过氧化物酶体
外对山羊外周血单核细胞功能的影响.畜牧与兽医，2014，46（5）：19-23
72. 张旭亮； 张振超； 苏苗苗； 孙悦； 李鹏飞； 徐立新； 宋小凯； 李祥瑞； 严若峰。
旋毛虫醛缩酶基因的克隆表达及重组蛋白酶比活性的分析。中国兽医科学，2014，44（05）：
497-502
73. 涂浩，赵星灿，杨占娜，李梦辉，徐立新，严若峰，宋小凯，李祥瑞. 猪重组 IL-2、IL-4
和 IFN-γ 对口蹄疫合成肽疫苗的免疫增强作用研究. 畜牧兽医学报 2015, 46(8):
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著作：
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