个人简介
教育经历:
2014.09 – 2019.06 浙江大学农业与生物技术学院,农学博士
2010.09 – 2014.06 华中农业大学植物科学与技术学院,农学学士
工作经历:
2021.10 – 至今 南京农业大学植物保护学院昆虫系,教授,博导
2019.08 – 2021.09 美国加州大学河滨分校昆虫系,博士后
承担课题:
南京农业大学高层次人才引进科研启动项目,2021-2026,在研,主持。
研究领域
昆虫分子毒理学
苏云金芽孢杆菌(Bacillus thuringiensis, Bt)在生长过程中会产生多种杀虫蛋白(Bt 毒素)。这些 Bt 毒素可以特异性地毒杀多种农业和卫生害虫,而对人类和其他生物无毒性。基于此,Bt 毒素被广泛地用于害虫防治,并带来显著的经济和社会效益。本课题组致力于解析 Bt 毒素杀虫机理。研究结果可为我国转Bt 抗虫作物的培育和田间布局以及害虫抗性治理提供重要理论基础。
近期论文
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1. Ya-Zhou He, Emre Aksoy, Yike Ding, Alexander S. Raikhel (2021). Hormonedependent activation and repression of microRNAs by the ecdysone receptor in
the Dengue vector mosquito Aedes aegypti. Proceedings of the National Academy of Sciences of the United States of America 118: e2102417118.
2. Ya-Zhou He, Yu-Meng Wang, Tian-Yan Yin, Wilmer Cuellar, Shu-Sheng Liu, XiaoWei Wang (2021). Gut-expressed vitellogenin facilitates the movement of a plant
virus across the midgut wall in its insect vector. mSystems 6, e00581-21.
3. Ya-Zhou He*, Yike Ding*, Xueli Wang, Zhen Zou, Alexander S. Raikhel (2021). E93confers steroid hormone responsiveness of digestive enzymes to promote bloodmeal digestion in the midgut of the mosquito Aedes aegypti. Insect Biochemistryand Molecular Biology 134: 103580. (*equal contribution).
4. Ya-Zhou He*, Yu-Meng Wang*, Tian-Yan Yin, Elvira Fiallo-Olivé, Yin-Quan Liu,Linda Hanley-Bowdoin, Xiao-Wei Wang (2020). A plant DNA virus replicates in
the salivary glands of its insect vector via recruitment of host DNA synthesismachinery. Proceedings of the National Academy of Sciences of the UnitedStates of America 117: 16928-16937. (*equal contribution).
5. Yu-Meng Wang, Ya-Zhou He, Xin-Tong Ye, Wen-Ze He, Shu-Sheng Liu, Xiao-WeiWang (2020). Whitefly HES1 binds to the intergenic region of Tomato yellow leaf curl China virus and promotes viral gene transcription. Virology 542: 54-62.
6. Yu-Meng Wang, Ya-Zhou He, Shu-Sheng Liu, Xiao-Wei Wang (2020). Mechanisms of plant virus transmission by the whitefly Bemisia tabaci (in Chinese). Chinese
Science Bulletin 65: 1463-1475.
7. Jing Wei*, Ya-Zhou He*, Qi Guo, Tao Guo, Yin-Quan Liu, Xue-Ping Zhou, ShuSheng Liu, Xiao-Wei Wang (2017). Vector development and vitellogenin determine the transovarial transmission of begomoviruses. Proceedings of theNational Academy of Sciences of the United States of America 114: 6746-6751. (*equal contribution).