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个人简介

学习/工作经历 2014年获美国奥本大学博士学位,2014-2017美国奥本大学从事博士后研究工作,2017年获聘中国海洋大学“青年英才工程”第一层次教授、博士生导师。 科研/教学情况 从事水产动物基因组学、生物信息学、分子遗传育种等领域的教学与科研工作。在水产动物基因组、转录组测序分析、分子标记开发、高密度芯片构建、重要经济性状精细遗传解析和基因组选择育种等领域系统开展工作。目前,已在国际知名学术刊物发表SCI论文100余篇。参编学术专著4部。 与国外多所高校、研究所保持密切合作关系,硕士期间表现优异者,有机会推荐至美国雪城大学(Syracuse University)、奥本大学(AuburnUniversity)、马里兰大学(UniversityofMaryland)等高校攻读博士学位或进行联合培养。主持科研项目主持国家自然基金面上项目、青年基金、中央高校基本科研业务费等,累计经费260余万元。

研究领域

1.水产动物基因组学、进化发育基因组生物学2.牡蛎分子遗传学、基因组辅助育种技术3.牡蛎高产抗病抗逆分子育种

水产动物基因组学、生物信息学、分子遗传育种

近期论文

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Li Y, Fu H, Zhang F, Ren L, Tian J, Li Q, Liu S#. Insulin-Like Peptide Receptor-Mediated Signaling Pathways Orchestrate Regulation of Growth in the Pacific Oyster (Crassostrea gigas), as Revealed by Gene Expression Profiles. International Journal of Molecular Sciences, 2021, 22:5259.Ren L, Li Y, Fu H, Zhang F, Yang B, Tan C, Li Q, Liu S#. A regulatory variant of tryptophan hydroxylase gene modulates transcription activity and biases growth rate in the Pacific oyster, Crassostrea gigas. Aquaculture, 2021, 542: 736906.Fu H, Jiao Z, Li Y, Tiang J, Ren L, Zhang F, Li Q, Liu S#. Transient Receptor Potential (TRP) Channels in the Pacific Oyster (Crassostrea gigas): Genome-Wide Identification and Expression Profiling after Heat Stress between C. gigasand C. angulata. International Journal of Molecular Sciences, 2021, 22(6):3222.Wang H, Yang B, Li X, Li Q, Liu S#. Screening of bacterial pathogens associated with mass summer mortality of the Pacific Oyster, Crassostrea gigas, in China. Aquaculture Reports, 2021, 20:100672Yang B, Zhai S, Li X, Li Q, Shan H, Liu S#. Identification of Vibrio alginolyticusas a causative pathogen associated with mass summer mortality of the Pacific Oyster (Crassostrea gigas) in China. Aquaculture, 2021, 535: 736363.Zhai S, Yang B, Zhang F, Li Q, Liu S#. Estimation of genetic parameters for resistance to Vibrio alginolyticusinfection in the Pacific oyster (Crassostrea gigas). Aquaculture, 2021, 736545.Doi: j.aquaculture.2021.736545Tian J, Jiao Z, Fu H, Qi L, Li Q, Liu N, Liu S#. Identification of cytochrome P450s and their expression profiles following cadmium exposure in the Pacific oyster, Crassostrea gigas. Aquaculture Reports, 2021, 19:100582.Han Z, Li Q, Xu C, Liu S, Yu, H, Kong L.QTL mapping for orange shell color and sex in the Pacific oyster (Crassostrea gigas). Aquaculture, 2021, 530, 735781.Chi Y, Li Q, Liu S, Kong L. Genetic parameters of growth and survival in the Pacific oyster,Crassostrea gigas, Aquaculture Research, 2021, 52:282–290.Li Y, Fu H, Zhang F, Ren L, Tiang J, Li Q, Liu S#. Identification, characterization, and expression profiles of insulin-like peptides suggest their critical roles in growth regulation of the Pacific oyster, Crassostrea gigas. Gene, 2021, 769: 145244.Yue C, Li Q, Yu H, Liu S, Kong L.Restriction site-associated DNA sequencing (RAD-seq) analysis in Pacific oyster Crassostrea gigasbased on observation of individual sex changes. Scientific Reports, 2020, 9873.Han Z, Li Q, Liu S, Kong L. Crossbreeding of three different shell color lines in the Pacific oyster reveals high heterosis for survival but low heterosis for 3growth. Aquaculture, 2020, 529, 735621.Zhang F, Hu B, Fu H, Jiao Z, Li Q#, Liu S#. Comparative transcriptome analysis reveals molecular basis underlying fast-growth of the selectively bred Pacific oyster, Crassostrea gigas. Frontiers in Genetics, 2019, 10:610.Bao L, Tian C, Liu S, Zhang Y, Elaswad A, Yuan Z, Khalil K, Sun F, Yang Y, Zhou T, Li N, Tan S, Zeng Q, Liu Y, Li Y, Li Y, Gao D, Dunham R, Davis K, Waldbieser G, Liu Z. The Y chromosome sequence of the channel catfish suggests novel sex determination mechanisms in teleost fish. BMC Biology, 2019, 17:6.Xu C, Li Q, Yu H, Liu S, Kong L, Chong J. Inheritance of shell pigmentation in Pacific oyster Crassostrea gigas. Aquaculture, 2019, 512:734249.Han Z, Li Q, Liu S, Yu H, Kong L. Genetic variability of an orange-shell mutant line of the Pacific oyster Crassostrea gigasduring artificial selection inferred from microsatellites and mitochondrial COI sequences. Aquaculture, 2019,508:159-166.Xu H, Li Q, Han Z, Liu S, Yu H, Kong L. Fertilization, survival and growth of hybrids between Crassostrea gigasand Crassostrea nippona. Aquaculture, 2019, 507(30):91-96.Zhang J, Li Q, Liu S, Yu H, Kong L. The effect of temperature on physiological energetics of a fast-growing selective strain and a hatchery population of the Pacific oyster (Crassostrea gigas). Aquaculture Research, 2018, 49:2844–2851.Zhou T, Li N, Jin Y, Zeng Q, Prabowo W, Liu Y, Tian C, Bao L, Liu S, Yuan Z, Fu Q, Gao S, Gao D, Dunham R, Shubin N, Liu Z. Chemokine C-C motif ligand 33 is a key regulator of teleost fish barbel development. PNAS, 2018, 115(22):E5018-E5027.Li N,Bao L,Zhou T,Yuan Z,Liu S,Dunham R,Li Y,Wang K,Xu X,Jin Y,Zeng Q,Gao S,Fu Q,Liu Y,Yang Y,Li Q,Meyer A,Gao D,Liu Z.Genome sequence of walking catfish (Clarias batrachus) provides insights into terrestrial adaptation. BMC Genomics, 2018, 19:952.Gao S*, Liu S*, Yao J, Li N, Yuan Z, Zhou T, Li Q, Liu Z. Genomic Organization and Evolution of Olfactory Receptors and Trace Amine-Associated Receptors in Channel Catfish. BBA -General Subjects, 2017, 1861:644-651.Gao S*, Liu S*, Yao J, Zhou T, Li N, Li Q, Dunham R, Liu Z. Taste Receptors and Gustatory Associated G proteins in Channel Catfish. CBP -Part D: Genomics and Proteomics 2017, 21:1-9.Geng X, Liu S, Yuan Z, Jiang Y, Zhi D, Liu Z. A Genome-Wide Association Study Reveals That Genes with Functions for Bone Development Are Associated with Body Conformation in Catfish. Marine Biotechnology, 2017, 19:570-578.Li Y*, Liu S*, Qin Z, Yao J, Jiang C, Song L, Dunham R, Liu Z. The serpin superfamily in channel catfish: Identification, phylogenetic analysis and expression profiling in mucosal tissues after bacterial infection. Developmental and Comparative Immunology, 2015, 49(2), 267-277.Nunes J*, Liu S*, Pértille F, Perazza C, Val V, Hilsdorf A, Liu Z, Coutinho L. Large- 4scale SNP discovery and construction of a high-density genetic map ofColossoma macropomumthough genotyping-by-sequencing. Scientific Reports. 2017, 7:46112.Wang X, Liu S, Jiang C, Geng X, Zhou T, Li N, Bao L, Li Y, Yao J, Yang Y, Jin Y, Dunham R, Liu Z. Multiple across-strain and within-strain QTLs suggest highly complex genetic architecturefor hypoxia tolerance in channel catfish. Molecular Genetics and Genomics, 2017, 292:63-76.Zhou T, Liu S, GengX, Jin Y, Jiang C, Bao L, Yao J, Zhang Y, Zhang J, Sun L, Wang X, Li N, Tan S, Liu Z. GWAS analysis of QTL for enteric septicemia of catfish and their involved genes suggest evolutionary conservation of a molecular mechanism of disease resistance. Molecular Genetics and Genomics, 2017, 292(1):231-242.Li Y, Liu S, Wang R, Qin Z and Liu Z. 2017. Bioinformatic considerations and approaches for high-density Linkage Mapping in Aquaculture. In: Bioinformatics in Aquaculture: Principles and Methods, Wiley and Blackwell Publishing, Ames, IA (Ed. Liu Z). Ch20: 356-379.Liu Sand Liu Z. 2017. Analysis of microRNAs and their target genes. In: Bioinformatics in Aquaculture: Principles and Methods, Wiley and Blackwell Publishing, Ames, IA (Ed. Liu Z). Ch13: 200-227.Liu Sand Liu Z. 2017. Introduction to Linux and command line tools for bioinformatics. In: Bioinformatics in Aquaculture: Principles and Methods, Wiley and Blackwell Publishing, Ames, IA (Ed. Liu Z). Ch1: 3-29.Liu S*, Li Y*, Qin Z, Geng X, Bao L, Kaltenboeck L, Kucuktas H, Dunham R, Liu Z. High-density interspecific genetic linkage mapping provides insights into genomic incompatibility between channel catfish and blue catfish. Animal Genetics, 2016, 47:81-90.Liu S, Zeng P and Liu Z. 2017. Gene set analysis of SNP data from genome-wide association studies. In: Bioinformatics in Aquaculture: Principles and Methods, Wiley and Blackwell Publishing, Ames, IA (Ed. Liu Z). Ch24: 434-459.Liu S, Zeng Q, Wang X and Liu Z. 2017. SNP array development, genotyping, data analysis, and applications. In: Bioinformatics in Aquaculture: Principles and Methods, Wiley and Blackwell Publishing, Ames, IA (Ed. Liu Z). Ch18: 308-337.Liu Z*, Liu S*, Yao J*, Bao L*, Zhang J*, Li Y*, Jiang C, Sun L, Zhang Y, Zhou T, Zeng Q, Fu Q, Gao S, Li N, Wang R, Koren S, Jiang Y, Zimin A, Xu P, Phillippy A, Geng X, Song L, Sun F, Li C, Wang X, Chen A, Jin Y, Yuan Z, Yang Y, Tan S, Peatman E, Lu J, Qin Z, Dunham R, Li Z, Sonstegard T, Feng J, Danzmann R, Schroeder S, Scheffler B, Duke M, Ballard L, Kucuktas H, Kaltenboeck L, Liu H, Armbruster J, Xie Y, Kirby M, Tian Y, Flanagan M, Mu W, Waldbieser G. The channel catfish genome sequence provides insights into evolution of scale formation in teleosts. Nature Communications, 2016, 7:11757.Yuan Z*, Liu S*, Yao J. Zeng Q, Tan S, Liu Z. Expression of Bcl-2 genes in channel catfish after bacterial infection and hypoxia stress. Developmental 5Comparative Immunology, 2016, 69:79-90.Zeng Q*, Liu S*, Yao J*, Zhang Y, Yuan Z, Jiang C, Chen A, Fu Q, Sun B, Dunham R, Liu Z. Transcriptome Display during Testicular Differentiation of Channel Catfish (Ictalurus punctatus) as Revealed by RNA-Seq Analysis. Biology of Reproduction, 2016, 95:19, 1-17.Liu S,Yao J, Zhang J, LiuZ. Next generation sequencing yields the complete mitochondrial genome of the striped raphael catfish, Platydoras armatulus(Siluriformes: Doradidae). Mitochondrial DNA, 2016, 27(3):1963-4.Liu S,Zhang J, Yao J, LiuZ. The complete mitochondrial genome of the armored catfish, Hypostomus plecostomus(Siluriformes: Loricariidae). Mitochondrial DNA, 2016, 27(3):1908-9.Jin Y, Liu S, Yuan Z, Yang Y, Tan S, Liu Z. 2015. Catfish genomic studies: Progress and perspectives. In: Genomics in Aquaculture, Elsevier (Eds.MacKenzie S and Jentoft S). Ch 4: 73-104.Li Y*, Liu S*, Qin Z, Waldbieser G, Wang R, Sun L, Bao L, Danzmann R, Dunham R, Liu Z. Construction of high-density SNP-based genetic map and its integration with BAC-based physical map in channel catfish. DNA Research, 2015, 22 (1): 39-52.Liu S*, Wang X*, Sun F, Zhang J, Feng J, Liu H, Rajendran KV, Sun L, Zhang Y, Jiang Y, Peatman E, Kaltenboeck L, KucuktasH and Liu Z. RNA-Seq reveals expression signatures of genes involved in oxygen transport, protein synthesis, folding and degradation in response to heat stress in catfish. Physiological Genomics, 2013, 45 (12):462-476.Liu S, Li Q, Liu Z. Genome-wide identification and evolutionary analysis of the ATP-binding cassette (ABC) transporter superfamily in catfish. PLoS ONE, 2013, 8(5): e63895.Liu S, Zhang Y, Sun F, Jiang Y, Wang R, Li C, Zhang J, Liu Z. 2012. Functional genomics research in aquaculture: principles and general approaches. In: Functional Genomics in Aquaculture, Wiley and Blackwell Publishing, Ames, IA (Eds. Saroglia M and Liu Z). Ch1: 1-40.Liu S, Zhang Y, Zhou Z, Waldbieser G, Sun F, Lu J, Zhang J, Jiang Y, Zhang H, Wang X, Rajendran KV, Kucuktas H, Peatman E, Liu Z. Efficient assembly and annotation of the transcriptome of catfish by RNA-Seq analysis of a doubled haploid homozygote. BMC Genomics. 2012, 13:595.Liu S, Zhou Z, Lu J, Sun F, Wang S, Liu H, Jiang Y, Kucuktas H, Kaltenboeck L, Peatman E, Liu Z. Generation of genome-scale gene-associated SNPs in catfish for the construction of a high-density SNP array. BMC Genomics. 2011, 12:53.

学术兼职

目前担任国际知名杂志MarineBiotechnology、Molecular Biology Reports编委(EditorialBoard),FrontiersinGenetics副主编(AssociateEditor)及十多个领域知名学术刊物审稿人。

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