研究领域
Biocatalysis
Bioenergy
Biosynthesis
Biotechnology
Catalysis
Chemical Biology
Drug discovery
Efficient chemical synthesis
Energy and Environment
Environmental remediation
Green chemistry
Organic Synthesis
Synthesis
Synthetic Biology
近期论文
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O'Reilly, E., Iglesias, C., Ghislieri, D., Hopwood, J., Galman, J. L., Lloyd, R. C. and Turner, N. J. A Regio- and Stereoselective É-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines. Angewandte Chemie (International Edition). 2014 February; 53(9): 2447-2456. eScholarID:222855 | DOI:10.1002/anie.201309208
M. Kalim Akhtar, Nicholas J. Turner, and Patrik R. Jones. Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities. Proceedings of the National Academy of Sciences. 2013; 110(1): 87-92. eScholarID:191976
O'Reilly, Elaine, Mark Corbett, Shahed Hussain, Paul P. Kelly, Dominique Richardson, S. L. Flitsch, and Nicholas J. Turner. Substrate Promiscuity of Cytochrome P450 RhF. The Royal Society of Chemistry; Catalysis Science & Technology (2013). 2013 April; eScholarID:191977 | DOI:10.1039/c3cy00091e
V. Köhler, Y. M. Wilson, M. Dürrenberger, D. Ghislieri, E. Churakova, T. Quinto, L. Knörr, D. Häussinger, F. Hollmann, N. J. Turner & T. R. Ward. Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes. Nature Chemistry. 2013; 5(2): 93-99. eScholarID:213338 | DOI:10.1038/nchem.1498
Nicholas J. Turner. Biocatalysis. Catal. Sci. Technol. 2012 June; 2: 1523-1523. eScholarID:185139 | DOI:10.1039/C2CY90030K
Simon C. Willies, Jemma L. White, Nicholas J. Turner. Development of a high-throughput screening method for racemase activity and its application to the identification of alanine racemase variants with activity towards l-arginine. Tetrahedron. 2012 September; 68(37): 7564-7567. eScholarID:185134 | DOI:10.1016/j.tet.2012.06.062
Dr. Ian Rowles, Dr. Kirk J. Malone, Dr. Laura L. Etchells, Dr. Simon C. Willies, Prof. Nicholas J. Turner. Directed Evolution of the Enzyme Monoamine Oxidase (MAO-N): Highly Efficient Chemo-enzymatic Deracemisation of the Alkaloid (±)-Crispine A. Chem.Cat.Chem. 2012 September; 4(9): 1259-1261. eScholarID:185128 | DOI:10.1002/cctc.201200202
Rajesh Kumar, Jim Cawley, Michael Karmilowicz, Carlos A. Martinez, Nathan Wymer, Bo Yuan, Franck Escalettes, Nicholas J. Turner, Johann H. Sattler, Katharina Tauber, Francesco G. Mutti, Wolfgang Kroutil. Oxidation of Alcohols. Practical Methods for Biocatalysis and Biotransformations 2. 2012 May; eScholarID:185129 | DOI:10.1002/9781119943426.ch6
Prof. Dr. Karlheinz Drauz Ph.D, Prof. Dr. Harald Gröger, Dr. Oliver May PhD and Nicholas J Turner. Oxidation of CN Bonds. Enzyme Catalysis in Organic Synthesis, Third Edition. 2012 April; eScholarID:185138 | DOI:10.1002/9783527639861.ch35
Simon Willies, Matthew D. Truppo, Christopher K. Savile, Jacob M. Janey, Jeffrey C. Moore, Gjalt W. Huisman, Gregory J. Hughes, Francesco G. Mutti, Christine S. Fuchs, Wolfgang Kroutil, Jennifer Hopwood, Matthew D. Truppo, Richard Lloyd, Nicholas J. Turner, Eun Young Hong, Minho Cha, Hyungdon Yun, Byung-Gee Kim and S. Stella, Anju Chadha. Reductive Amination. Practical Methods for Biocatalysis and Biotransformations 2. 2012 May; eScholarID:185137 | DOI:10.1002/9781119943426.ch2
Elaine O’Reilly, Suzanne J Aitken, Gideon Grogan, Paul P Kelly, Nicholas J Turner, and Sabine L Flitsch. Regio- and stereoselective oxidation of unactivated C–H bonds with Rhodococcus rhodochrous. Beilstein J Org Chem. 2012 April; 8: 496-500. eScholarID:185133 | DOI:10.3762/bjoc.8.56
John Whittall, Peter W. Sutton, Valentin Köhler, Bas Groenendaal, Kevin R. Bailey, Anass Znabet, James Raferty, Madeleine Helliwell, Nicholas J. Turner, Kristian Geitner, Uwe T. Bornscheuer, Gonzalo de Gonzalo, Vicente Gotor, Shuvendu Das, John P. N. Rosazza, Aashrita Rajagopalan, Francesco G. Mutti and Wolfgang Kroutil. Selective Oxidation. Practical Methods for Biocatalysis and Biotransformations 2. 2012 May; eScholarID:185135 | DOI:10.1002/9781119943426.ch7