Goodacre, Roy - The University of Manchester

个人简介

Educated in University of Bristol , UK where he was awarded his BSc in Microbiology and his PhD in analytical methods applied to microbiological problems. After which he did a three year PDRA in University of Wales, Aberystwyth, UK and then four years as a Wellcome Trust Fellow where he investigated chemometrics and artificial neural networks for the analysis of spectroscopic data. Following this he was appointed a Lecturer in Microbiology. He moved in Feb 2003 to take up the position of Reader in Analytical Science in the School of Chemistry , The University of Manchester, UK. His current position since Aug 2005 is as Professor of Biological Chemistry.

研究领域

Roy Goodacre's research interests are broadly within analytical biotechnology and systems biology. He has over 18 years experience of advanced data analysis applied to spectroscopic, mass spectrometric and metabolomics data; over 18 years experience in mass spectrometry (MS), and over 11 years in vibrational spectroscopy.

近期论文

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J. William Allwood, William Cheung, Yun Xu, Roland Mumm, Ric C.H. De Vos Catherine Deborde, Benoit Biais, Mickael Maucourt, Yosef Berger, Arthur A. Schaffer, Dominique Rolin, Annick Moing, Robert D. Hall, Royston Goodacre. Metabolomics in melon: A new opportunity for aroma analysis. Phytochemistry. 2014 January; eScholarID:235320 Najla AlMasoud, Yun Xu, Nicoletta Nicolaou, Royston Goodacre. Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species. Analytica Chimica Acta. 2014 June; eScholarID:238384 Mabbott S, Eckmann A, Casiraghi C, Goodacre R. 2p or not 2p: tuppence-based SERS for the detection of illicit materials. The Analyst. 2013 January; 138(1): 118-22. eScholarID:184188 | PMID:23095916 | DOI:10.1039/c2an35974j Allwood J, Parker D, Beckmann M, Draper J, Goodacre R. Fourier Transform Ion Cyclotron Resonance mass spectrometry for plant metabolite profiling and metabolite identification. Methods in molecular biology (Clifton, N.J.). 2012; 860: 157-76. eScholarID:184191 | PMID:22351177 | DOI:10.1007/978-1-61779-594-7_11 Allwood J, Heald J, Lloyd A, Goodacre R, Mur L. Separating the inseparable: the metabolomic analysis of plant-pathogen interactions. Methods in molecular biology (Clifton, N.J.). 2012; 860: 31-49. eScholarID:184197 | PMID:22351169 | DOI:10.1007/978-1-61779-594-7_3 Correa E, Sletta H, Ellis D, Hoel S, Ertesvåg H, Ellingsen T, Valla S, Goodacre R. Rapid reagentless quantification of alginate biosynthesis in Pseudomonas fluorescens bacteria mutants using FT-IR spectroscopy coupled to multivariate partial least squares regression. Analytical and bioanalytical chemistry. 2012 July; 403(9): 2591-9. eScholarID:184196 | PMID:22585056 | DOI:10.1007/s00216-012-6068-6 Dunn W, Summers A, Brown M, Goodacre R, Lambie M, Johnson T, Wilkie M, Davies S, Topley N, Brenchley P. Proof-of-principle study to detect metabolic changes in peritoneal dialysis effluent in patients who develop encapsulating peritoneal sclerosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2012 June; 27(6): 2502-10. eScholarID:184195 | PMID:22294777 | DOI:10.1093/ndt/gfr662 Ellis D, Brewster V, Dunn W, Allwood J, Golovanov A, Goodacre R. Fingerprinting food: current technologies for the detection of food adulteration and contamination. Chemical Society reviews. 2012 September; 41(17): 5706-27. eScholarID:184186 | PMID:22729179 | DOI:10.1039/c2cs35138b Ellis D, Goodacre R. Metabolomics-assisted synthetic biology. Current opinion in biotechnology. 2012 February; 23(1): 22-8. eScholarID:184192 | PMID:22104721 | DOI:10.1016/j.copbio.2011.10.014 Levene C, Correa E, Blanch E, Goodacre R. Enhancing surface enhanced Raman scattering (SERS) detection of propranolol with multiobjective evolutionary optimization. Analytical chemistry. 2012 September; 84(18): 7899-905. eScholarID:184189 | PMID:22934935 | DOI:10.1021/ac301647a Mabbott S, Correa E, Cowcher D, Allwood J, Goodacre R. Optimization of Parameters for the Quantitative Surface-Enhanced Raman Scattering Detection of Mephedrone Using a Fractional Factorial Design and a Portable Raman Spectrometer. Analytical chemistry. 2012 December; eScholarID:184194 | PMID:23198960 | DOI:10.1021/ac302542r Mabbott S, Larmour I, Vishnyakov V, Xu Y, Graham D, Goodacre R. The optimisation of facile substrates for surface enhanced Raman scattering through galvanic replacement of silver onto copper. The Analyst. 2012 June; 137(12): 2791-8. eScholarID:184198 | PMID:22558633 | DOI:10.1039/c2an35323g Nicolaou N, Xu Y, Goodacre R. Detection and quantification of bacterial spoilage in milk and pork meat using MALDI-TOF-MS and multivariate analysis. Analytical chemistry. 2012 July; 84(14): 5951-8. eScholarID:184187 | PMID:22698768 | DOI:10.1021/ac300582d Prest J, Baldock S, Fielden P, Goddard N, Goodacre R, O'Connor R, Treves Brown B. Miniaturised free flow isotachophoresis of bacteria using an injection moulded separation device. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 August; 903: 53-9. eScholarID:184193 | PMID:22819202 | DOI:10.1016/j.jchromb.2012.06.040 Rehman S, Xu Y, Dunn W, Day P, Westerhoff H, Goodacre R, Bayat A. Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing. Molecular bioSystems. 2012 September; 8(9): 2274-88. eScholarID:184190 | PMID:22772395 | DOI:10.1039/c2mb25173f Vaughan A, Dunn W, Allwood J, Wedge D, Blackhall F, Whetton A, Dive C, Goodacre R. Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion. Analytical chemistry. 2012 November; 84(22): 9848-57. eScholarID:184199 | PMID:23072438 | DOI:10.1021/ac302227c