张卫 - 山东师范大学 - 化学化工与材料科学院

个人简介

张卫，山东禹城人，博士，教授，博士生导师。2019年度山东省杰出青年基金获得者，全国黄大年式教学科研团队骨干成员, 2015年度山东省属高校优秀青年基金获得者。2012年毕业于南开大学化学学院分析化学专业获博士学位，同年进入山东师范大学化学化工与材料科学学院工作至今。主要从事仿生荧光传感材料的设计、制备及应用研究。针对复杂样品中目标蛋白质的定量分析问题，开展了一系列高灵敏的荧光检测方法研究，围绕细胞内重要的活性功能分子，发展了系列的荧光成像分析方法，取得了多项创新性和系统性的科研成果。在学术期刊发表论文40余篇，SCI他引2000余次，其中以第一或通讯作者发表在Angew. Chem. Int. Ed. 4篇，Chem. Sci. 2篇，Anal. Chem. 6篇。目前，主持国家自然科学基金面上项目2项，国家重点研发计划项目子课题1项，山东省杰出青年基金项目1项。2019年获得山东省自然科学奖二等奖。此外，张卫教授还曾获山东师范大学 “杰出青年”、山东师范大学优秀共产党员等荣誉

研究领域

主要从事仿生荧光传感材料的设计、制备及应用研究。针对复杂样品中目标蛋白质的定量分析问题，开展了一系列高灵敏的荧光检测方法研究，围绕细胞内重要的活性功能分子，发展了系列的荧光成像分析方法，取得了多项创新性和系统性的科研成果。

近期论文

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Jin Li, Na Zhao, Wei Zhang,* Ping Li, Xia Yin, Wen Zhang, Hui Wang, and Bo Tang*. Assessing the Progression of Early Atherosclerosis Mice Using a Fluorescence Nanosensor for the Simultaneous Detection and Imaging of pH and Phosphorylation. Angew. Chem. Int. Ed. 2023, 62, e202215178. Jun Lu, Zhongyao Jiang, Jie Ren, Wei Zhang*, Ping Li, Zhenzhen Chen, Wen Zhang, Hui Wang, and Bo Tang*. One-Pot Synthesis of Multifunctional Carbon-Based Nanoparticle-Supported Dispersed Cu2+ Disrupts Redox Homeostasis to Enhance CDT. Angew. Chem. Int. Ed. 2022, 61, e202114373. (Hot Paper) Wei Zhang, Jie Ren, Jun Lu, Ping Li, Wen Zhang, Hui Wang, and Bo Tang*. Elucidating the Relationship between ROS and Protein Phosphorylation through In Situ Fluorescence Imaging in the Pneumonia Mice. Anal. Chem., 2021, 93, 10907-10915. Wei Zhang, Xiaolei Liu, Ping Li, Wen Zhang, Hui Wang, and Bo Tang*. In Situ Fluorescence Imaging of the Levels of Glycosylation and Phosphorylation by a MOF-Based Nanoprobe in Depressed Mice. Anal. Chem., 2020, 92, 3716-3721. Wei Zhang, Hui Zhang, Mengqi Wang, Ping Li, Caifeng Ding, Wen Zhang, Hui Wang, and Bo Tang*. Copolymer-Based Fluorescence Nanosensor for In Situ Imaging of Homocysteine in the Liver and Kidney of Diabetic Mice. Anal. Chem., 2020, 92, 16221-16228. Jiheng Xu,† Hui Zhang,† Wei Zhang*, Ping Li, Wen Zhang, Hui Wang and Bo Tang*. Fluorescence nanosensor for in situ detection of phosphate and alkaline phosphatase in parathyroid dysfunction mice. Chem. Commun., 2020, 56, 2431-2434. Wei Zhang, Xiaolei Liu, Ping Li, Wen Zhang, Hui Wang, Bo Tang* Cellular fluorescence imaging based on resonance energy transfer. TRAC-Trend. Anal. Chem. 2020, 123, 115742. Jun Lu, Li Yang, Wei Zhang,* Ping Li, Xiaonan Gao, Wen Zhang, Hui Wang and Bo Tang * Photodynamic therapy for hypoxic solid tumors via Mn-MOF as a photosensitizer. Chem. Commun., 2019, 55, 10792. Wei Zhang, Jun Lu, Xiaonan Gao, Ping Li*, Wen Zhang, Yu Ma, Hui Wang, Bo Tang*. Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano-MOF with CuII as Active Center. Angew. Chem. Int. Ed., 2018, 57, 4891-4896. Wei Zhang*, Ruixia Wang, Wei Liu, Xin Wang, Ping Li*, Wen Zhang, Hui Wang and Bo Tang*. Te-containing carbon dots for fluorescence imaging of superoxide anion in mice during acute strenuous exercise or emotional changes. Chem. Sci., 2018, 9, 721-727. Wei Zhang*, Jiheng Xu, Ping Li, Xiaonan Gao, Wen Zhang, Hui Wang and Bo Tang*. Treatment of hyperphosphatemia based on specific interaction between phosphorus and active center Zr(IV) of nano-MOFs. Chem. Sci., 2018, 9, 7483-7487. Wei Zhang, Junqing Kang, Ping Li*, Lu Liu, Hui Wang and Bo Tang*. Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe. Chem. Commun., 2016, 52, 13991-13994. Wei Zhang, Junqing Kang, Ping Li*, Hui Wang, and Bo Tang*. Dual Signaling Molecule Sensor for Rapid Detection of Hydrogen Sulfide Based on Modified Tetraphenylethylene. Anal. Chem., 2015, 87, 8964-8969. Wei Zhang, Wei Liu, Ping Li*, Fang Huang, Hui Wang, and Bo Tang*. Rapid-Response Fluorescent Probe for Hydrogen Peroxide in Living Cells Based on Increased Polarity of C-B Bonds. Anal. Chem., 2015, 87, 9825-9828. Wei Zhang, Wei Liu, Ping Li*, Junqing Kang, Jiaoyang Wang, Hui Wang and Bo Tang*. Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo. Chem. Commun., 2015, 51, 10150-10153. Wei Zhang, Wei Liu, Ping Li*, Haibin Xiao, Hui Wang, and Bo Tang*. A Fluorescence Nanosensor for Glycoproteins with Activity Based on the Molecularly Imprinted Spatial Structure of the Target and Boronate Affinity. Angew. Chem. Int. Ed., 2014, 53, 12489-12493.