个人简介
张鹏,男,博士,副教授。2003年毕业于沈阳药科大学,获药学(英语)学士学位;2006年于同校获药物分析硕士学位,同年留校任教;2010年于同校获药剂学博士学位。2012年被聘为沈阳药科大学药学院副教授。作为课题负责人主持了国家自然科学基金项目1项,辽宁省教育厅科学技术研究项目1项,辽宁省自然科学基金项目1项,沈阳药科大学科研专项基金1项。参与国家十一五重大专项研究1项(阿糖胞苷-C5’-O-L-缬氨酸酯的研制);参与2015版《中国药典》四种制剂辅料质量标准的起草工作(碳酸丙烯酯,山梨酸钾、辛酸钠、辛酸);参与完成国家自然科学基金项目5项以及其他沈阳市科技计划项目和横向合作课题多项。截至2016年,在国内外学术刊物上发表科研论文30余篇,其中SCI收载25篇。
研究领域
研究方向一:药物分析新技术研究
研究方向二:药品质量一致性评价研究
研究方向三:生物药剂学和药物动力学研究
近期论文
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1.ZhangP,LingG,SunJ,SunY,PuX,WangZ,HeZ.Determinationofmitoxantroneinratplasmabyliquidchromatography-tandemmassspectrometrymethod:Applicationtoapharmacokineticstudy.JChromatogrB.2010;878(24):2260-2265.(SCI,IF2.687)
2.ZhangP,LingG,SunJ,ZhangT,YuanY,SunY,WangZ,HeZ.MultifunctionalnanoassembliesforvincristinesulfatedeliverytoovercomemultidrugresistancebyescapingP-glycoproteinmediatedefflux.Biomaterials.2011;32(23):5524-5533.(SCI,IF8.387)
3.ZhangP,LingG,PanX,SunJ,ZhangT,PuX,YinS,HeZ.Novelnanostructuredlipid-dextransulfatehybridcarriersovercometumormultidrugresistanceofmitoxantronehydrochloride.Nanomedicine.2012;8(2):185-193.(SCI,IF5.671)
4.LingG,ZhangT,ZhangP,SunJ,HeZ.Synergisticandcompletereversalofthemultidrugresistanceofmitoxantronehydrochloridebythree-in-onemultifunctionallipid-sodiumglycocholatenanocarriersbasedonsimultaneousBCRPandBcl-2inhibition.IntJNanomedicine.2016;11:4077-4091.(SCI,IF4.32)
5.LingG,ZhangT,ZhangP,SunJ,HeZ.Nanostructuredlipid-carrageenanhybridcarriers(NLCCs)forcontrolleddeliveryofmitoxantronehydrochloridetoenhanceanticanceractivitybypassingtheBCRP-mediatedefflux.DrugDevIndPharm.2016;42(8):1351-1359.(SCI,IF2.429)
6.SongS,ZhaoD,SunJ,MiaoQ,LiuX,WangY,ZhongL,XuM,ZhangP.DevelopmentofaUPLC-MS/MSmethodforthedeterminationoflomefloxacininrabbitaqueoushumoranditsapplicationtoapharmacokineticstudy.JChromatogrB.2016.1033-1034:187-192.(SCI,IF2.687)
7.YuQ,YuQ,WuL,SunJ,MaP,LiuX,DongWandZhangP.ValidatedStability-indicatingRP-HPLCMethodfortheDeterminationofParecoxibSodiumandDegradationImpuritiesinBulkDrug.CurrentPharmaceuticalAnalysis.2016;12(4):1-8.(SCI,IF0.885)
8.WangJ,WuL,KouL,XuM,SunJ,WangY,FuQ,ZhangP,HeZ.Novelnanostructuredenoxaparinsodium-PLGAhybridcarriersovercometumormultidrugresistanceofdoxorubicinhydrochloride.IntJPharm.2016;513(1-2):218-226.(SCI,IF3.994)
9.WuL,SunJ,SuX,YuQ,YuQ,ZhangP.Areviewaboutthedevelopmentoffucoidaninantitumoractivity:Progressandchallenges.CarbohydrPolym.2016;154:96-111.(SCI,IF4.219)
10.WangJ,LiL,WuL,SunB,DuY,SunJ,WangY,FuQ,ZhangP,HeZ.Developmentofnovelself-assembledES-PLGAhybridnanoparticlesforimprovingoralabsorptionofdoxorubicinhydrochloridebyP-gpinhibition:Invitroandinvivoevaluation.EurJPharmSci.2017;99:185-192.(SCI,IF3.773)