Ecofriendly Method to Dissolve Chitosan in Plain Water,ACS Biomaterials Science & Engineering

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Ecofriendly Method to Dissolve Chitosan in Plain Water
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2019-11-13 , DOI: 10.1021/acsbiomaterials.9b00695
Boxuan Li _{1,

2} , Juan Wang ₁ , Mahmoud E. Moustafa ₁ , Hu Yang ₁

Affiliation

Chitosan is an important and abundant natural-based polymer, and it has broad applications. However, dissolving chitosan in plain water is a challenge, which mostly limits the biomedical applications of chitosan materials. Herein, we report an ecofriendly dissolution method to obtain a plain water-based chitosan solution for the first time. In this method, dissolving chitosan in ionic liquid followed by overnight freezing at −20 °C and subsequent solvent exchange with plain water at room temperature results in a stable chitosan dispersion in water with nanosize, namely water-based, chitosan pseudosolution. The overall process is ecofriendly. This new method augments the quality and processability of chitosan solutions used in manufacturing and bioprocessing and promotes the biomedical applications of chitosan-based products.

中文翻译：

一种在平原水中溶解脱乙酰壳多糖的环保方法

壳聚糖是重要且丰富的天然聚合物，具有广泛的应用。然而，将壳聚糖溶解在纯水中是一个挑战，这在很大程度上限制了壳聚糖材料的生物医学应用。在此，我们首次报道了一种生态友好的溶解方法，以得到纯净的水基壳聚糖溶液。在这种方法中，将脱乙酰壳多糖溶解在离子液体中，然后在-20°C下过夜冷冻，然后在室温下与普通水交换溶剂，可将脱乙酰壳多糖稳定分散在纳米级水中，即水基脱乙酰壳多糖假溶液。整个过程是环保的。这种新方法提高了用于制造和生物加工的壳聚糖溶液的质量和可加工性，并促进了基于壳聚糖的产品的生物医学应用。

更新日期：2019-11-14

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