Rapid Construction of the ABCE Tetracyclic Tertiary Amine Skeleton in Daphenylline Enabled by an Amine–Borane Complexation Strategy,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Rapid Construction of the ABCE Tetracyclic Tertiary Amine Skeleton in Daphenylline Enabled by an Amine–Borane Complexation Strategy
Organic Letters ( IF 4.9 ) Pub Date : 2019-04-22 00:00:00 , DOI: 10.1021/acs.orglett.9b01021
Meng Deng ₁ , Yanmin Yao ₁ , Xiaohu Li ₁ , Nan Li ₁ , Xiao Zhang ₁ , Guangxin Liang ₁

Affiliation

A synthetically challenging tetracyclic tertiary amine framework in the Daphniphyllum alkaloid daphenylline was established in a six-step sequence featuring an intermolecular Diels–Alder cycloaddition/oxidative aromatization sequence. The utilization of an amine–borane complexation strategy is the key to successful transformations on our tertiary amine substrates.

中文翻译：