Five chiral metal–organic coordination compounds (CMOCCs), {[Cu4O(Lvcz)2Br4]·H2O}n (1), {[Cd(HLvcz)2(NO3)2]·0.25H2O}n (2), {[Cu2(HLvcz)2I2]·H2O}n (3), {[Ag(HLvcz)2]CF3SO3}n (4), and {[Co2(HLvcz)(bdc)2(dmf)2]·dmf·3H2O}n (5; HLvcz = voriconazole, bdc = terephthalic acid), have been successfully prepared and structurally characterized. The chiral drug ligand voriconazole exhibits diverse modes of coordination in the five complexes, resulting in the formation of various architectures and properties. Complex 1 is a tetranuclear cluster, complex 2 exhibits a 1D double-strand chain structure in which hydrogen-bonding interactions lead to a 3D supramolecular network, complex 3 is a 1D chain structure with two different types of rings based on the rhombic dimer Cu2I2, complex 4 is a 2D structure with 63 topology that contains four types of C–H···F hydrogen bonds, and complex 5 affords a 3D framework with sxa topology. Their properties, such as chirality, second-order nonlinear optical (NLO) effects, ferroelectric behavior and dielectric anomalies, have been investigated in the solid state.

中文翻译：

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药物伏立康唑手性金属-有机配位配合物的配位模式、结构和性质的多样性

五种手性金属有机配位化合物 (CMOCCs), {[Cu4O(Lvcz)2Br4]·H2O}n (1), {[Cd(HLvcz)2(NO3)2]·0.25H2O}n (2), {[ Cu2(HLvcz)2I2]·H2O}n (3), {[Ag(HLvcz)2]CF3SO3}n (4), 和 {[Co2(HLvcz)(bdc)2(dmf)2]·dmf·3H2O} n (5; HLvcz = 伏立康唑，bdc = 对苯二甲酸)，已成功制备和结构表征。手性药物配体伏立康唑在五种配合物中表现出不同的配位模式，从而形成各种结构和特性。配合物 1 是四核簇，配合物 2 表现出一维双链结构，其中氢键相互作用导致 3D 超分子网络，配合物 3 是一维链结构，具有基于菱形二聚体 Cu2I2 的两种不同类型的环，complex 4 是一个 2D 结构的 63 拓扑结构，包含四种类型的 C–H…F 氢键，complex 5 提供了具有 sxa 拓扑结构的 3D 框架。它们的性质，例如手性、二阶非线性光学 (NLO) 效应、铁电行为和介电异常，已在固态下进行了研究。