Prerequisites of Isopeptide Bond Formation in Microcystin Biosynthesis,ChemBioChem

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Prerequisites of Isopeptide Bond Formation in Microcystin Biosynthesis
ChemBioChem ( IF 2.6 ) Pub Date : 2017-10-27 02:00:36 , DOI: 10.1002/cbic.201700389
Sabine Meyer ₁ , Andi Mainz ₂ , Jan-Christoph Kehr ₁ , Roderich D. Süssmuth ₂ , Elke Dittmann ₁

Affiliation

Isopeptide bond formation: In vitro characterization of nonribosomal peptide synthetase modules containing β-Me-d-Asp and d-Glu in the carboxylic side chains of the potent toxin microcystin provides new insight into isopeptide bond formation and the collaborative interaction of adenylation and condensation domains in substrate activation.

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