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Laser‐Induced Cell Detachment and Patterning with Photodegradable Polymer Substrates
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2011-03-23 , DOI: 10.1002/anie.201007310 George Pasparakis , Theodore Manouras , Alexandros Selimis , Maria Vamvakaki , Panagiotis Argitis
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2011-03-23 , DOI: 10.1002/anie.201007310 George Pasparakis , Theodore Manouras , Alexandros Selimis , Maria Vamvakaki , Panagiotis Argitis
A glimpse of light is all it takes: Polymers that undergo main‐chain scission at remarkably low photolysis energies were developed as efficient photodegradable substrates for safe laser‐mediated cell detachment and patterning. The polymers, which contain acetal or ketal units in their backbone along with suitable absorbing groups, underwent fast degradation to release live cells upon irradiation with an excimer laser (see picture).
中文翻译:
激光诱导的细胞分解和可光降解聚合物基板的图案化
一目了然:能够以极低的光解能量进行主链断裂的聚合物被开发为有效的可光降解基质,可安全地进行激光介导的细胞分离和图案化。聚合物在主链上含有缩醛或缩酮单元以及合适的吸收基团,经过准分子激光辐照后迅速降解,释放出活细胞(见图)。
更新日期:2011-03-23
中文翻译:
激光诱导的细胞分解和可光降解聚合物基板的图案化
一目了然:能够以极低的光解能量进行主链断裂的聚合物被开发为有效的可光降解基质,可安全地进行激光介导的细胞分离和图案化。聚合物在主链上含有缩醛或缩酮单元以及合适的吸收基团,经过准分子激光辐照后迅速降解,释放出活细胞(见图)。