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Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2016-11-18 02:51:22 , DOI: 10.1002/anie.201610558
Hang Li 1 , Pranav Balan 2 , Akos Vertes 1
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Visualizing the interaction zoneRapidly emerging microbial resistance to antibiotics is a growing concern for the treatment of infectious diseases. In their Communication on page 15035 ff., A. Vertes et al. describe the application of laser ablation electrospray ionization (LAESI) in combination with mass spectrometry (MS) to gain deeper molecular insight into microbe–antibiotic interactions. LAESI-MS imaging enhances the quantitative nature of antibiotic susceptibility testing, while significantly reducing the required incubation time.

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可视化相互作用区对于细菌感染,快速增长的微生物耐药性日益引起人们的关注。A. Vertes等人在其第15035页及其后的通讯中。描述了激光消融电喷雾电离(LAESI)与质谱(MS)结合的应用,以更深入地了解微生物与抗生素的相互作用。LAESI-MS成像增强了抗生素敏感性测试的定量性质,同时大大减少了所需的孵育时间。
更新日期:2016-11-18
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