INTRODUCTION Global migration has increased in recent decades due to war, conflict, persecutions, and natural disasters, but also secondary to increased opportunities related to work or study. Migrants' risk of tuberculosis (TB) differs by reasons for migration, socioeconomic status, mode of travel and TB risk in transit, TB incidence and healthcare provision in country of origin. Despite advances in TB care for migrants and new treatment strategies, decisions for the management of migrants at risk of TB often rely on expert opinions, rather than clinical evidence. METHODS A systematic literature search was conducted, studies were mapped to different recommendation groups and included studies were synthesized by meta-analysis where appropriate. Current evidence on diagnosis of active TB in migrants entering the European Union /European Economic Area (EU/EEA) &UK including the clinical presentation and diagnostic delay, treatment outcomes of drug susceptible TB, prevalence and treatment outcomes of multidrug/rifampicin-resistant (MDR/RR)-TB and TB/HIV co-infection was summarised. A consensus process was used based on the evidence. RESULTS We document a higher vulnerability of migrants for TB, including an increased risk of extrapulmonary TB, MDR/RR-TB, TB/HIV co-infection and worse TB treatment outcomes compared to host populations. Consensus recommendations include screening of migrants for TB/ latent TB infection (LTBI) according to country data; a minimal package for TB care in drug susceptible and MDR/RR-TB; implementation of migrant-sensitive strategies; free healthcare and preventive treatment for migrants with HIV co-infection. CONCLUSION Dedicated care for TB prevention and treatment in migrant populations within the EU/EEA &UK is essential.

中文翻译：

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欧洲成年移民的结核病：TBnet 共识声明。


引言 近几十年来，由于战争、冲突、迫害和自然灾害，全球移民有所增加，但也次要原因是与工作或学习相关的机会增加。移民患结核病 （TB） 的风险因移民原因、社会经济地位、旅行方式和过境结核病风险、结核病发病率和原籍国的医疗保健供应而异。尽管在移民结核病护理和新的治疗策略方面取得了进展，但管理有结核病风险的移民的决定往往依赖于专家意见，而不是临床证据。方法 进行系统的文献检索，将研究映射到不同的推荐组，并在适当的情况下通过 meta 分析综合纳入的研究。总结了进入欧盟/欧洲经济区 （EU/EEA） 和英国的移民诊断活动性结核病的当前证据，包括临床表现和诊断延迟、药物敏感结核病的治疗结果、多药/利福平耐药 （MDR/RR）-TB 和 TB/HIV 合并感染的患病率和治疗结果。根据证据使用了共识过程。结果我们记录了移民患结核病的易感性更高，包括与宿主人群相比，肺外 TB、MDR/RR-TB、TB/HIV 合并感染的风险增加和更差的结核病治疗结果。共识建议包括根据国家数据对移民进行结核病/潜伏性结核病感染 （LTBI） 筛查;对药物敏感和耐多药/RR-结核病的结核病护理提供最低限度的一揽子计划;实施对移民敏感的策略;为合并感染 HIV 的移民提供免费医疗保健和预防性治疗。结论 对欧盟/欧洲经济区和英国移民人群的结核病预防和治疗进行专门护理是必不可少的。