Objectives To evaluate the acceptability and performance of an organ inventory as an alternative to asking about gender and/or sex assigned at birth in cancer screening. Methods We fielded an online, self-administered survey to a convenience sample of English- or Spanish-speaking transgender and gender-diverse (TGD), intersex, and cisgender people (>/=15 years) in the US. The survey contained an organ inventory developed with community input and questions regarding acceptability. The primary outcome was organ inventory acceptability by the four-item Acceptability of Intervention Measure (AIM). Additional outcomes included inter-method screening agreement between the organ inventory, gender, and sex assigned at birth. Results In 2022, 333 eligible individuals completed the survey; 44.4% cisgender, 34.2% TGD, and 14.1% intersex. Overall, participants rated the organ inventory as acceptable (median AIM score = 18/20, IQR: 16-20). Most (73%) found it easy to understand, and comfortable to complete (65%). Cancer screening eligibility varied based on the method used; relying solely on gender or sex data would have missed some eligible participants that the organ inventory identified. Conclusions Using an organ inventory as an alternative to gender or sex-based screening questions was acceptable, and has implications for addressing cancer screening disparities.

中文翻译：

---

跨性别认同和双性人身份进行癌症筛查的器官清单的可接受性


目的 评价器官清单作为癌症筛查中询问性别和/或出生时分配的性别的替代方案的可接受性和性能。方法 我们对美国讲英语或西班牙语的跨性别者和性别多元化 （TGD）、双性人和顺性别者 （>/=15 岁） 的便利样本进行了一项在线、自我管理的调查。该调查包含根据社区意见和有关可接受性的问题开发的器官清单。主要结局是四项干预措施可接受性 （AIM） 的器官清单可接受性。其他结局包括器官清单、性别和出生时分配的性别之间的方法间筛选一致性。结果 2022 年，333 名符合条件的个人完成了调查;44.4% 顺性别者、34.2% TGD 和 14.1% 双性人。总体而言，参与者将器官清单评为可接受 （中位 AIM 评分 = 18/20，IQR： 16-20）。大多数人 （73%） 认为它易于理解，并且完成起来很舒适 （65%）。癌症筛查资格因使用的方法而异;仅依靠性别或性别数据会错过器官清单确定的一些符合条件的参与者。结论 使用器官清单作为基于性别或性别的筛查问题的替代方案是可以接受的，并且对解决癌症筛查差异具有影响。