Effects of very early hyperoxemia on neurologic outcome after out-of-hospital cardiac arrest: A secondary analysis of the TTM-2 trial,Resuscitation

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Effects of very early hyperoxemia on neurologic outcome after out-of-hospital cardiac arrest: A secondary analysis of the TTM-2 trial
Resuscitation ( IF 6.5 ) Pub Date : 2024-12-07 , DOI: 10.1016/j.resuscitation.2024.110460
Filippo Sanfilippo, Agnieszka Uryga, Cristina Santonocito, Janus Christian Jakobsen, Gisela Lilja, Hans Friberg, Pedro David Wendel-Garcia, Paul J. Young, Glenn Eastwood, Michelle S. Chew, Johan Unden, Matthew Thomas, Anders M Grejs, Matt P. Wise, Andreas Lundin, Jacob Hollenberg, Naomi Hammond, Manoj Saxena, Annborn Martin, Robert Bánszky, Fabio Silvio Taccone, Josef Dankiewicz, Niklas Nielsen, Florian Ebner, Jan BeloholaveK, Matthias Hanggi, Luca Montagnani, Nicolo’ Patroniti, Chiara Robba, for the TTM-2 investigators

Hyperoxemia is common in patients resuscitated after out-of-hospital cardiac arrest (OHCA) admitted to the intensive care unit (ICU) and may increase the risk of mortality. However, the effect of hyperoxemia on functional outcome, specifically related to the timing of exposure to hyperoxemia, remains unclear.

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