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Pro-arrhythmic potential of proton-pump inhibitors
Nature Reviews Cardiology ( IF 41.7 ) Pub Date : 2024-12-09 , DOI: 10.1038/s41569-024-01107-w
Pietro Enea Lazzerini, Riccardo Accioli, Pier Leopoldo Capecchi, Maurizio Acampa

Population studies have reported that proton-pump inhibitors (PPIs) increase cardiovascular mortality, at least in part owing to an increased propensity for life-threatening arrhythmias, but these findings have largely been ignored. We propose a series of recommendations for prescribers of PPIs to ensure a balance of the benefits against the potential arrhythmic risks.

中文翻译:


质子泵抑制剂的促心律失常电位



人群研究报告称,质子泵抑制剂 (PPI) 会增加心血管死亡率,至少部分原因是危及生命的心律失常倾向增加,但这些发现在很大程度上被忽视了。我们为 PPI 的处方者提出了一系列建议,以确保在益处与潜在的心律失常风险之间取得平衡。
更新日期:2024-12-10
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