Wang et al. demonstrate that lactate derived from glioblastoma stem cells, microglia and macrophages drives histone lactylation, activating immunosuppressive transcriptional programs and upregulating CD47, to suppress phagocytosis.

中文翻译：

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乳酸有酸味


Wang 等人证明，来自胶质母细胞瘤干细胞、小胶质细胞和巨噬细胞的乳酸驱动组蛋白乳酸化，激活免疫抑制转录程序并上调 CD47，以抑制吞噬作用。