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Antiviral target compound profile for pandemic preparedness
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2024-12-02 , DOI: 10.1038/s41573-024-01102-3 James F. Demarest, Ruxandra Draghia-Akli, Tomas Cihlar, Kenneth Bradley, John A. T. Young, Richa Chandra, Sujata Vaidyanathan, Margaret Chu-Moyer, Christopher L. Lynch, Andrew Campbell, Kumar Singh Saikatendu, John P. Bilello, Yoshihiko Murata, Marnix van Loock, Aeron C. Hurt, Timothy Tellinghuisen, Lee Ruggiero, Richard Mackman, Nina M. Hill, John C. Pottage
中文翻译:
用于大流行防范的抗病毒靶标化合物概况
更新日期:2024-12-02
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2024-12-02 , DOI: 10.1038/s41573-024-01102-3 James F. Demarest, Ruxandra Draghia-Akli, Tomas Cihlar, Kenneth Bradley, John A. T. Young, Richa Chandra, Sujata Vaidyanathan, Margaret Chu-Moyer, Christopher L. Lynch, Andrew Campbell, Kumar Singh Saikatendu, John P. Bilello, Yoshihiko Murata, Marnix van Loock, Aeron C. Hurt, Timothy Tellinghuisen, Lee Ruggiero, Richard Mackman, Nina M. Hill, John C. Pottage
The recent experiences with the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have demonstrated the urgent need for a structured approach towards accelerated and more effective discovery, development and delivery of vaccines, therapeutics, and diagnostics to minimize the overall impact of the next pandemic (see Related links). This urgency is further highlighted by the recent World Health Organization (WHO) declaration of a public health emergency of international concern for mpox (see Related links).
中文翻译:
用于大流行防范的抗病毒靶标化合物概况
最近由严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 引起的大流行的经验表明,迫切需要一种结构化的方法,以加速和更有效地发现、开发和提供疫苗、治疗和诊断方法,以最大限度地减少下一次大流行的整体影响(参见相关链接)。世界卫生组织 (WHO) 最近宣布 mpox 为国际关注的突发公共卫生事件,进一步强调了这种紧迫性(参见相关链接)。