Obesity has become a global pandemic that is associated with a range of metabolic disorders. Traditional treatment options, such as lifestyle modification and anti-obesity medications, often exhibit limited efficacy and can lead to long-term weight gain, especially upon discontinuation of the medication. Although bariatric surgery is effective, its accessibility is constrained, and only a small percentage of eligible patients receive this intervention. Over the past two decades, endoscopic bariatric and metabolic therapies (EBMTs) have emerged as minimally invasive and effective alternatives for managing obesity and its related comorbidities. This article reviews primary gastric and small bowel EBMTs, their mechanisms of action, key supporting literature, and the metabolic outcomes associated with each device and procedure.

中文翻译：

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肥胖和代谢疾病的内窥镜管理。


肥胖已成为一种与一系列代谢紊乱相关的全球流行病。传统的治疗方案，如生活方式改变和抗肥胖药物，往往疗效有限，并可能导致长期体重增加，尤其是在停药后。尽管减肥手术有效，但其可及性受到限制，只有一小部分符合条件的患者接受这种干预。在过去的二十年里，内窥镜减肥和代谢疗法 （EBMTs） 已成为控制肥胖及其相关合并症的微创有效替代方案。本文回顾了原发性胃和小肠 EBMTs、它们的作用机制、关键支持文献以及与每种设备和手术相关的代谢结局。