Modern nanotechnologies provide various possibilities for efficiently delivering drugs to biological targets. This review focuses on using functionalized gold nanoparticles (GNPs) as a drug delivery platform. Owing to their exceptional size and surface characteristics, GNPs are a perfect drug delivery vehicle for targeted and selective distribution. Several in vitro and in vivo tests have shown how simple it is to tailor these particles to administer chemical medications straight to tumors. The GNP surface can also be coated with ligands to modify drug release or improve selectivity. Moreover, the pharmacological activity can be enhanced by using the photothermal characteristics of the particles.

中文翻译：

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使用金纳米颗粒的药物递送


现代纳米技术为有效地将药物递送到生物靶标提供了多种可能性。本综述重点介绍使用功能化金纳米颗粒 （GNP） 作为药物递送平台。由于其特殊的尺寸和表面特性，GNP 是靶向和选择性分布的完美药物递送载体。几项体外和体内测试表明，定制这些颗粒以将化学药物直接施用于肿瘤是多么简单。GNP 表面也可以包被配体，以修饰药物释放或提高选择性。此外，利用颗粒的光热特性可以提高药理活性。