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Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials
The Lancet Diabetes & Endocrinology ( IF 44.0 ) Pub Date : 2024-11-25 , DOI: 10.1016/s2213-8587(24)00271-7 Prof Sunil V Badve PhD, Anika Bilal MD, Matthew M Y Lee PhD, Prof Naveed Sattar MD, Prof Hertzel C Gerstein MD, Prof Christian T Ruff MD MPH, Prof John J V McMurray MD, Prof Peter Rossing MD, Prof George Bakris MD, Prof Kenneth W Mahaffey MD, Prof Johannes F E Mann MD, Prof Helen M Colhoun MD, Prof Katherine R Tuttle MD, Prof Richard E Pratley MD, Prof Vlado Perkovic PhD
The Lancet Diabetes & Endocrinology ( IF 44.0 ) Pub Date : 2024-11-25 , DOI: 10.1016/s2213-8587(24)00271-7 Prof Sunil V Badve PhD, Anika Bilal MD, Matthew M Y Lee PhD, Prof Naveed Sattar MD, Prof Hertzel C Gerstein MD, Prof Christian T Ruff MD MPH, Prof John J V McMurray MD, Prof Peter Rossing MD, Prof George Bakris MD, Prof Kenneth W Mahaffey MD, Prof Johannes F E Mann MD, Prof Helen M Colhoun MD, Prof Katherine R Tuttle MD, Prof Richard E Pratley MD, Prof Vlado Perkovic PhD
GLP-1 receptor agonists reduce the risk of major adverse cardiovascular events (MACE) and can also have kidney benefits. However, whether GLP-1 receptor agonists improve clinically important kidney outcomes remains uncertain. We aimed to comprehensively assess the effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes by performing a meta-analysis of randomised controlled trials.
中文翻译:
GLP-1 受体激动剂对肾脏和心血管疾病结局的影响:随机对照试验的荟萃分析
GLP-1 受体激动剂可降低主要不良心血管事件 (MACE) 的风险,并且还可以对肾脏有益。然而,GLP-1 受体激动剂是否能改善临床上重要的肾脏结局仍不确定。我们旨在通过对随机对照试验进行荟萃分析,全面评估 GLP-1 受体激动剂对肾脏和心血管疾病结局的影响。
更新日期:2024-11-25
中文翻译:
GLP-1 受体激动剂对肾脏和心血管疾病结局的影响:随机对照试验的荟萃分析
GLP-1 受体激动剂可降低主要不良心血管事件 (MACE) 的风险,并且还可以对肾脏有益。然而,GLP-1 受体激动剂是否能改善临床上重要的肾脏结局仍不确定。我们旨在通过对随机对照试验进行荟萃分析,全面评估 GLP-1 受体激动剂对肾脏和心血管疾病结局的影响。