Sympathetic overactivation contributes to hypertension. Renal denervation can reduce blood pressure. In the deoxycorticosterone acetate (DOCA)-salt model of hypertension, salt consumption contributes to high blood pressure. A report in Kidney International finds selective ablation of renal sensory afferent nerves diminishes self-directed saline intake in the DOCA-salt rat. This suggests that these sensory nerves input to centers in the brain, amplifying salt intake. If translatable, renal denervation may have an unanticipated benefit of reducing the drive to consume salty foods in patients with poorly controlled hypertension.

中文翻译：

---

肾脏会影响对盐的渴望吗？


交感神经过度激活会导致高血压。肾去神经支配可以降低血压。在高血压的醋酸脱氧皮质酮 （DOCA） 盐模型中，盐摄入会导致高血压。Kidney International 上的一份报告发现，肾感觉传入神经的选择性消融减少了 DOCA 盐大鼠的自主盐水摄入量。这表明这些感觉神经输入到大脑中的中枢，放大了盐的摄入量。如果可翻译，肾去神经支配可能具有意想不到的好处，即减少高血压控制不佳的患者食用咸味食物的动力。