Pediatric donors are underutilized for simultaneous pancreas-kidney transplantation due to concerns about technical complications and inadequate islet and/or renal mass. We analyzed our experience with simultaneous en bloc kidney and pancreas transplantation using pediatric donors on 8 consecutive adult patients from 1997-2018. En bloc kidney transplants were implanted intraperitoneally and contralaterally to right-sided pancreas grafts. All patients became insulin-independent immediately; with 1 case of delayed kidney function and 1 case of insulin resistance; there were no graft thromboses. Donor age averaged 5.0 ± 1.7 years and weight 19.8 ± 4.8 kg; recipient age averaged 46.6 ± 12.8 years and body mass index 25.2 ± 3.8 kg/m2. Postoperative creatinine, glucose, and C-peptide reflected good graft function. Simultaneous en bloc kidney and pancreas transplantation is a safe technique providing excellent long-term glycemic control and kidney function to adult recipients.

中文翻译：

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来自儿科供体的同步整块肾脏和胰腺移植：选择、手术策略、管理和结果


由于担心技术并发症以及胰岛和/或肾脏肿块不足，儿科供体未被用于胰肾同步移植。我们分析了 1997-2018 年连续 8 例成年患者使用儿科供体同时进行整块肾脏和胰腺移植的经验。将整块肾移植植入右侧胰腺移植物的腹膜内和对侧。所有患者立即变得胰岛素独立;肾功能延迟 1 例，胰岛素抵抗 1 例;没有移植物血栓形成。供体平均年龄为 5.0 ± 1.7 岁，体重 19.8 ± 4.8 公斤;接受者平均年龄为 46.6 ± 12.8 岁，体重指数 25.2 ± 3.8 kg/m2。术后肌酐、葡萄糖和 C 肽反映良好的移植物功能。同时整块肾脏和胰腺移植是一种安全的技术，可为成年受者提供出色的长期血糖控制和肾功能。