OBJECTIVES The objective of this study was to quantify trends (2008-2019) in stroke outcomes by race-ethnicity. METHODS Patients with ischemic stroke from a population-based study were interviewed at 90 days to assess outcomes. Linear regression with multiple imputation and inverse probability weighting was used to model trends. RESULTS The median age was 66 years (n = 1,449); 61% were Mexican American (MA). QOL remained stable with no race-ethnic difference in trends (p for time*race-ethnicity interaction = 0.81). Neurologic outcomes improved for MA (p < 0.01) but not non-Hispanic White (NHW) persons with stroke (p = 0.23) with no race-ethnic difference in trends (p for interaction = 0.23). For functional outcomes, trends were stable and then improved in MA persons with stroke (p for interaction = 0.01), whereas trends were stable in NHW persons with stroke (p = 0.52). For cognitive outcomes, there was little change in NHW persons with stroke (p = 0.50); in MA persons with stroke, there was improvement followed by decline and then improvement (p = 0.03). No race-ethnic differences in trends in functional (p for interaction = 0.51) or cognitive (p for interaction = 0.21) outcomes were noted. DISCUSSION Outcome improvements were noted in MA but not NHW persons with stroke; race-ethnic differences were not present in 2019. Understanding factors contributing to favorable trends in MA persons may be informative for improving outcomes in all persons.

中文翻译：

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按种族-民族划分的短期卒中结果随时间的变化。


目的 本研究的目的是按种族-民族量化中风结局的趋势 （2008-2019）。方法 在一项基于人群的研究中，缺血性卒中患者在 90 天时接受访谈以评估结果。使用具有多重插补和逆概率加权的线性回归对趋势进行建模。结果 中位年龄为 66 岁 （n = 1,449）;61% 是墨西哥裔美国人 （MA）。QOL 保持稳定，趋势没有种族-民族差异 （p） 时间*种族-民族互动 = 0.81）。MA （p < 0.01） 的神经系统结局有所改善，但非西班牙裔白人 （NHW） 中风患者的神经系统结局没有改善 （p = 0.23），趋势没有种族-民族差异 （p for interaction = 0.23）。对于功能结果，MA 中风患者的趋势稳定，然后有所改善 （交互作用 p = 0.01），而 NHW 中风患者的趋势稳定 （p = 0.52）。对于认知结果，NHW 中风患者几乎没有变化 （p = 0.50）;在 MA 中风患者中，先改善，然后下降，然后改善 （p = 0.03）。未注意到功能 （交互 p = 0.51） 或认知 （交互 p = 0.21） 结果趋势的种族-民族差异。讨论 MA 患者结局改善，但 NHW 中风患者未观察到;2019 年不存在种族-民族差异。了解导致 MA 患者良好趋势的因素可能有助于改善所有人的结局。