PTEN hamartoma tumor syndrome (PHTS), DICER1-related tumor predisposition (DICER1) and tuberous sclerosis complex (TSC) are rare conditions which each increase risk for distinct spectra of benign and malignant neoplasms throughout childhood and adulthood. Surveillance considerations for each of these conditions focus on patient and family education, early detection and multidisciplinary care. In this manuscript, we present updated surveillance recommendations and considerations for children and adolescents with PHTS, DICER1 and TSC and provide suggestions for further research in each of these conditions.

中文翻译：

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PTEN 错构瘤综合征、DICER1 相关肿瘤易感性和结节性硬化症综合征的儿科监测建议更新


PTEN 错构瘤肿瘤综合征 （PHTS）、DICER1 相关肿瘤易感性 （DICER1） 和结节性硬化症 （TSC） 是罕见的疾病，它们都会增加整个儿童期和成年期良恶性肿瘤不同谱系的风险。这些疾病的监测考虑集中在患者和家庭教育、早期发现和多学科护理上。在本手稿中，我们提出了针对患有 PHTS、DICER1 和 TSC 的儿童和青少年的最新监测建议和注意事项，并为这些情况的进一步研究提供了建议。