The study by Vivanti et al.1 represents a significant contribution to research on autism screening. This cluster-randomized controlled trial (RCT) sought to determine whether the implementation of the Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F)2 during routine well-child check-ups could improve the early identification and referral rates for autism spectrum disorder (ASD). The trial included a diverse sample of pediatric practices, randomly assigned to either an experimental group, in which the M-CHAT-R/F was systematically implemented with high fidelity, or a control group that continued with usual care practices.

中文翻译：

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社论：自闭症筛查工具的批判性检查：呼吁解决假阴性


Vivanti 等人1 的研究代表了对自闭症筛查研究的重大贡献。这项整群随机对照试验 （RCT） 旨在确定在常规儿童健康检查期间实施改良的幼儿自闭症检查表，修订并随访 （M-CHAT-R/F）2 是否可以提高自闭症谱系障碍 （ASD） 的早期识别和转诊率。该试验包括不同的儿科实践样本，随机分配到实验组，其中 M-CHAT-R/F 以高保真度系统地实施，或继续常规护理实践的对照组。