PURPOSE To compare interindividual differences in visual performance of an advanced monofocal with a non-diffractive extended depth of focus intraocular lens using a mini-monovision approach. DESIGN Single-center, randomized, controlled, double-masked study. METHODS In total, 48 patients (96 eyes) with bilateral age-related cataract were enrolled. One group received an advanced monofocal IOL RAO200E (RayOne EMV™, Rayner), and the other group a non-diffractive extended depth of focus IOL DFT015 (Acrysof IQ Vivity™, Alcon) in both eyes. Target refraction for both groups was mini-monovision. After 3 months, monocular and binocular distance corrected and uncorrected distance (CDVA/UDVA), intermediate (DCIVA/UIVA) and near visual acuity (CDNVA/UNVA), contrast sensitivity, binocular defocus curves, halometry and a quality of vision questionnaire have been compared. RESULTS Binocular mean CDVA, DCIVA at 66cm and DCNVA at 40cm were -0.10±0.10, 0.15±0.11 and 0.32±0.16 logMAR for the RAO200E and -0.10±0.10, 0.12±0.10 and 0.27±0.16 logMAR for the DFT015, respectively with no significant difference. A significant difference could be shown for the dominant eye in monocular DCIVA, DCNVA, and dominant and non-dominant eye in monocular UNVA with 0.28±0.14, 0.48±0.22, 0.46±0.21 and 0.41±0.20 logMAR for the RAO200E and 0.14±0.10 (p=0.023), 0.35±0.16 (p=0.008) 0.30±0.14 (p=0.001) and 0.21±0.10 (p=0.003) logMAR for the DFT015, respectively. Significantly smaller halo size in the RAO200E group and significantly better distance corrected defocus curve at -2.5 (p=0.031), -2.0 (p=0.03) and -1 diopters (0.03) of defocus in the DFT015 group could be shown. CONCLUSIONS Distance corrected or uncorrected binocular visual acuity for far, intermediate and near distance between the advanced monofocal IOL RAO200E and the non-diffractive extended depth of focus IOL DFT015, when compared in a mini-monovision setting, showed no significant differences.

中文翻译：

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使用微型单视方法比较高级单焦点和非衍射扩展焦深人工晶状体：比较用于微型单视的高级人工晶状体。


目的 使用微型单视方法比较高级单焦点与非衍射扩展焦深人工晶状体在视觉性能方面的个体间差异。设计 单中心、随机、对照、双盲研究。方法 共纳入 48 例双侧年龄相关性白内障患者 （96 只眼）。一组接受高级单焦点 IOL RAO200E （RayOne EMV™， Rayner），另一组接受双眼非衍射扩展焦深 IOL DFT015 （Acrysof IQ Vivity™， Alcon）。两组的目标屈光都是微小单视。3 个月后，比较了单眼和双眼距离校正和未校正距离 （CDVA/UDVA）、中间 （DCIVA/UIVA） 和近视力 （CDNVA/UNVA）、对比敏感度、双眼散焦曲线、盐测定和视力质量问卷。结果 双眼平均 CDVA、66 cm 处 DCIVA 和 40 cm 处 DCNVA 分别为 -0.10±0.10、0.15±0.11 和 0.32±0.16 log RAO200E MAR，DFT015 分别为 -0.10±0.10、0.12±0.10 和 0.27±0.16 logMAR，差异无统计学意义。单眼 DCIVA、DCNVA 中的主眼以及单眼 UNVA 中的主眼和非主眼存在显著差异，RAO200E 的 logMAR 为 0.28±0.14、0.48±0.22、0.46±0.21 和 0.41±0.20 logMAR，DFT015 为 0.14±0.10 （p=0.023）、0.35±0.16 （p=0.008）、0.30±0.14 （p=0.001） 和 0.21±0.10 （p=0.003） logMAR， 分别。在 DFT015 组中，RAO200E组的光晕大小明显较小，在 -2.5 （p=0.031）、-2.0 （p=0.03） 和 -1 屈光度 （0.03） 处可以显示距离校正散焦曲线明显更好。 结论 高级单焦点 IOL RAO200E和非衍射扩展焦深 IOL DFT015 之间的远、中、近距离距离矫正或未矫正双眼视力，在微型单视设置中进行比较时，没有显示出显着差异。