Liver fibrosis staging is challenging in patients with obesity and metabolic dysfunction–associated steatotic liver disease (MASLD). Liver biopsies are invasive, whereas noninvasive tests such as vibration-controlled transient elastography (VCTE) can be inaccurate in patients with obesity. We hypothesized that EUS-guided shear wave elastography (EUS-SWE) is more accurate for liver fibrosis staging in patients with MASLD and obesity; the aim of this pilot study was to test this hypothesis and establish optimal fibrosis stage cutoffs for EUS-SWE.

中文翻译：

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EUS 引导剪切波弹性成像用于肥胖和代谢功能障碍相关脂肪性肝病患者纤维化筛查：一项初步研究（附视频）


肥胖和代谢功能障碍相关脂肪性肝病 （MASLD） 患者的肝纤维化分期具有挑战性。肝活检是侵入性的，而无创检查（如振动控制瞬时弹性成像 （VCTE））在肥胖患者中可能不准确。我们假设 EUS 引导的剪切波弹性成像 （EUS-SWE） 对 MASLD 和肥胖患者的肝纤维化分期更准确;这项试点研究的目的是检验这一假设并确定 EUS-SWE 的最佳纤维化分界线。