Having more refined mouse models of metabolic dysfunction-associated steatotic liver disease (MASLD; also known as nonalcoholic fatty liver disease) will help to advance research into this disease. In their study, Jeong and colleagues use streptozotocin together with a high-fat diet for 6–60 weeks to investigate the progression from MASLD to hepatocellular carcinoma.

中文翻译：

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人类肝病建模：从脂肪性肝病到 MASH-HCC


拥有更精细的代谢功能障碍相关脂肪性肝病 （MASLD;也称为非酒精性脂肪性肝病） 小鼠模型将有助于推进对这种疾病的研究。在他们的研究中，Jeong 及其同事将链脲佐菌素与高脂肪饮食一起使用 6-60 周，以研究从 MASLD 到肝细胞癌的进展。