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Mpox Hepatic and Pulmonary Lesions in HIV/Hepatitis B Virus Co-Infected Patient, France
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2024-10-20 , DOI: 10.3201/eid3011.241331 Ruxandra Calin, Claire Périllaud-Dubois, Stéphane Marot, Khaldoun Kerrou, Gilles Peytavin, Marwa Bachir, Anne Laure Kirch, Ludovic Lassel, Vincent Fallet, Joel Gozlan, Jean Baptiste Pain, Patricia Senet, Olivier Ferraris, Sébastien Bine, Mathieu Hubert, Olivier Schwartz, Laurence Morand-Joubert, Gilles Pialoux
中文翻译：
法国 HIV/乙型肝炎病毒合并感染患者的猴痘肝脏和肺部病变
更新日期：2024-10-21
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2024-10-20 , DOI: 10.3201/eid3011.241331 Ruxandra Calin, Claire Périllaud-Dubois, Stéphane Marot, Khaldoun Kerrou, Gilles Peytavin, Marwa Bachir, Anne Laure Kirch, Ludovic Lassel, Vincent Fallet, Joel Gozlan, Jean Baptiste Pain, Patricia Senet, Olivier Ferraris, Sébastien Bine, Mathieu Hubert, Olivier Schwartz, Laurence Morand-Joubert, Gilles Pialoux
We report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had <200 CD4+ cells/mm3, pulmonary and hepatic necrotic lesions, persistent viremia, and nasopharyngeal excretion. Clinical outcome was favorable after 90 days of tecovirimat treatment and administration of human vaccinia immunoglobulins.
中文翻译：
法国 HIV/乙型肝炎病毒合并感染患者的猴痘肝脏和肺部病变
我们报告了一例在法国一名 HIV/乙型肝炎病毒合并感染患者中持续播散性 mpox 在 >6 个月内演变的病例，该患者具有 <200 CD4+ 细胞/mm3、肺和肝坏死病变、持续性病毒血症和鼻咽排泄。tecovirimat 治疗和人痘苗免疫球蛋白给药 90 天后，临床结局良好。
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