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Tumor hypoxia: long ignored but now detectable and potentially actionable
Clinical Cancer Research ( IF 10.0 ) Pub Date : 2024-10-16 , DOI: 10.1158/1078-0432.ccr-24-2626 Ralph P. Mason
Clinical Cancer Research ( IF 10.0 ) Pub Date : 2024-10-16 , DOI: 10.1158/1078-0432.ccr-24-2626 Ralph P. Mason
Oxygen-enhanced MRI was successfully applied to 24 patients with HPV-associated oropharyngeal cancer. This prospective trial rigorously evaluated reproducibility and changes with respect to tumor radiation. Analyses compared hypoxic volumes and hypoxic fractions. It represents important progress in developing a practical approach to assessing tumor hypoxia in patients noninvasively.
中文翻译:
肿瘤缺氧:长期以来被忽视,但现在可检测到并可能采取行动
氧增强 MRI 成功应用于 24 例 HPV 相关口咽癌患者。这项前瞻性试验严格评估了肿瘤放疗的可重复性和变化。分析比较了低氧体积和低氧分数。它代表了开发一种无创评估患者肿瘤缺氧的实用方法的重要进展。
更新日期:2024-10-16
中文翻译:
肿瘤缺氧:长期以来被忽视,但现在可检测到并可能采取行动
氧增强 MRI 成功应用于 24 例 HPV 相关口咽癌患者。这项前瞻性试验严格评估了肿瘤放疗的可重复性和变化。分析比较了低氧体积和低氧分数。它代表了开发一种无创评估患者肿瘤缺氧的实用方法的重要进展。