We are thankful that Igl and Constant¹ are joining the creation of the virtuous cycle for the use of Bayesian approaches in clinical trials. Their comments help to expand the considerations from the original paper² and bring additional perspectives to bear on Bayesian approaches. We are in general agreement with their Correspondence. We will make a few additional comments on topics in the order they appear in their Correspondence.

中文翻译：

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回复 “药物开发中的贝叶斯方法：继续良性循环”

我们非常感谢 Igl 和 Constant¹ 加入创建在临床试验中使用贝叶斯方法的良性循环。他们的评论有助于扩展原始论文² 中的考虑，并为贝叶斯方法带来更多视角。我们大致同意他们的通信。我们将按照主题在通信中出现的顺序对主题进行一些补充评论。