To coincide with the 20th anniversary of Nature Reviews Gastroenterology & Hepatology, we asked three experts to reflect on the past, present and future of metabolic dysfunction-associated steatotic liver disease (MASLD) research and clinical management. They comment on how MASLD research and clinical management has changed over the past 20 years, the strengths and limitations of the MASLD field today, and their predictions for progress over the next 20 years. In this Viewpoint, Alina M. Allen, Juan Pablo Arab and Vincent Wai-Sun Wong reflect on the past, present and future of metabolic dysfunction-associated steatotic liver disease (MASLD) research and clinical management.

中文翻译：

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MASLD：一种不断变化的疾病


为了配合Nature Reviews胃肠病学和肝病学的20周年纪念，我们邀请了三位专家来反思代谢功能障碍相关脂肪性肝病（MASLD）研究和临床管理的过去、现在和未来。他们评论了 MASLD 研究和临床管理在过去 20 年中的变化、当今 MASLD 领域的优势和局限性，以及他们对未来 20 年进展的预测。在这个观点中，Alina M. Allen、Juan Pablo Arab 和 Vincent Wai-Sun Wong 反思了代谢功能障碍相关脂肪性肝病 （MASLD） 研究和临床管理的过去、现在和未来。