Colorectal cancer is associated with substantial morbidity and mortality worldwide. Detection of early colorectal cancer is possible through approved screening tests but overall adherence is quite low. Implementation of effective noninvasive options could increase screening uptake and prevent a significant number of deaths. Noninvasive early cancer detection can potentially be achieved using a liquid biopsy. In this issue of Cancer Research, Cao and colleagues report on a novel multidimensional fragmentomics assay, named FRAGTECT, for colorectal cancer detection in circulating cell-free DNA with promising results. See related article by Cao et al., p. 3286

中文翻译：

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结直肠癌筛查的下一个前沿：血液检测


结直肠癌与全世界的高发病率和死亡率相关。通过批准的筛查测试可以检测早期结直肠癌，但总体依从性相当低。实施有效的非侵入性选择可以提高筛查率并防止大量死亡。使用液体活检可以实现无创早期癌症检测。在本期《癌症研究》中，Cao 及其同事报告了一种名为 FRAGTECT 的新型多维片段组学测定，用于循环游离 DNA 中的结直肠癌检测，并取得了有希望的结果。参见Cao等人的相关文章，第17页。 3286