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Relmapirazin, a new exogenous filtration marker, and more widespread use of measured GFR.
Kidney International ( IF 14.8 ) Pub Date : 2024-10-01 , DOI: 10.1016/j.kint.2024.07.019
Marcelle Tuttle,Andrew S Levey

Plasma or urinary clearance of exogenous filtration markers is required for assessment of measured glomerular filtration rate. Although multiple methods are available, none is widely used because of their complexity, each has measurement error, and standardization is limited. Recently, a study validated the plasma clearance of a new exogenous filtration marker, relmapirazin, which can be detected by its transdermal fluorescence, potentially simplifying the procedure and increasing access to measured glomerular filtration rate.

中文翻译:


Relmapirazin,一种新的外源性滤过标记物,以及测量 GFR 的更广泛使用。



评估测量的肾小球滤过率需要血浆或尿液清除外源性滤过标志物。尽管有多种方法可用,但由于其复杂性,每种方法都存在测量误差,并且标准化受到限制,因此没有一种方法被广泛使用。最近,一项研究验证了一种新的外源性滤过标记物瑞马哌嗪的血浆清除率,该标记物可以通过其透皮荧光进行检测,从而可能简化程序并增加测量肾小球滤过率的机会。
更新日期:2024-09-23
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