Rodents are ubiquitous and typically unwelcome dwellers in human habitats worldwide, infesting homes, farm fields, and agricultural stores and potentially shedding disease-causing microbes into the most human-occupied of spaces. Of the vertebrate animal taxa that share pathogens with us, rodents are the most abundant and diverse, with hundreds of species of confirmed zoonotic hosts, some of which have nearly global distributions. However, only 12% of rodent species are known to be sources of pathogens that also infect people, and those rodents that do are now recognized as tending to share a suite of predictable traits. Here, we characterize those traits and explore them in the context of three emerging or reemerging rodent-borne zoonotic diseases of people: Lassa fever, Lyme disease, and plague.

中文翻译：

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啮齿动物传播的人畜共患疾病的新模式


啮齿动物在世界各地的人类栖息地中无处不在，通常是不受欢迎的居民，它们侵扰家庭、农田和农产品商店，并可能将致病微生物传播到人类居住最多的空间。在与我们共享病原体的脊椎动物类群中，啮齿动物是数量最多、种类最多的，已确认的人畜共患宿主有数百种，其中一些几乎分布于全球。然而，已知只有 12% 的啮齿类动物是也会感染人类的​​病原体来源，而那些确实感染人类的​​啮齿类动物现在被认为往往具有一系列可预测的特征。在这里，我们描述了这些特征，并在三种新出现或重新出现的啮齿类动物传播的人类人畜共患疾病的背景下探讨它们：拉沙热、莱姆病和鼠疫。