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New clinical trials in CUP and a novel paradigm in cancer classification
Nature Reviews Clinical Oncology ( IF 81.1 ) Pub Date : 2024-09-11 , DOI: 10.1038/s41571-024-00942-7
Elie Rassy 1, 2 , Fabrice André 1, 3
Affiliation  

Precision oncology has reached a milestone as data from two trials in which molecular profiling guided both site-specific and tumour-agnostic therapies indicate improved survival outcomes in patients with cancer of unknown primary. These findings can also be extrapolated and support the use of tissue-agnostic approaches in general, and also suggest that the tissue of origin might have a role in the agnostic classification of cancers and their response to treatment.

中文翻译:


CUP 的新临床试验和癌症分类的新范式



精准肿瘤学已经达到了一个里程碑,因为两项试验的数据表明,分子分析指导部位特异性和肿瘤无关性治疗的患者生存结果得到改善。这些发现也可以外推并支持一般使用组织无关方法,并且还表明起源组织可能在癌症的不可知分类及其对治疗的反应中发挥作用。
更新日期:2024-09-11
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