This population-based cross-sectional study analyzed electronic health record data of pregnant individuals in an integrated health care delivery system in California to examine changes in prenatal cannabis use through self-report and urine toxicology testing during standard prenatal care between 2012 (n=33,546) and 2022 (n=43,415), and to test whether trends differed by race and ethnicity or age. The prevalence of prenatal cannabis use increased from 5.5% (95% CI, 5.3-5.8%) in 2012 to 9.0% (95% CI, 8.7-9.2%) in 2022 (adjusted prevalence ratio [aPR] 1.82, 95% CI, 1.72-1.92), with similar increases by toxicology test (aPR 1.70, 95% CI, 1.60-1.81) and self-report (aPR 2.12, 95% CI, 1.95-2.30). The increase in prevalence varied significantly across racial and ethnic and age groups, with the highest prevalence among Black individuals and those aged 13-24 across years. Although rates increased more slowly among groups with the highest prevalence of use, disparities persisted over time.

中文翻译：

---

2012 年至 2022 年孕妇产前大麻使用的变化。


这项基于人群的横断面研究分析了加利福尼亚州综合医疗保健服务系统中孕妇的电子健康记录数据，以通过 2012 年 （n=33,546） 和 2022 年（n=43,415）标准产前保健期间的自我报告和尿液毒理学测试来检查产前大麻使用的变化，并测试趋势是否因种族和民族或年龄而异。产前大麻使用的流行率从 2012 年的 5.5%（95% CI，5.3-5.8%）增加到 2022 年的 9.0%（95% CI，8.7-9.2%）（调整后患病率 [aPR] 1.82,95% CI，1.72-1.92），毒理学测试（aPR 1.70,95% CI，1.60-1.81）和自我报告（aPR 2.12,95% CI，1.95-2.30）也有类似的增加。患病率的增加因种族、民族和年龄组而异，其中黑人和 13-24 岁人群的患病率最高。尽管在使用率最高的群体中，比率的增加较慢，但随着时间的推移，差异仍然存在。