Persistence of Lugol-unstaining is Associated With an Increased Risk of Progression to Malignancy in the Esophagus,Clinical Gastroenterology and Hepatology

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Persistence of Lugol-unstaining is Associated With an Increased Risk of Progression to Malignancy in the Esophagus
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-08-22 , DOI: 10.1016/j.cgh.2024.07.030
Mengfei Liu ₁ , Zeyu Yan ₁ , Zifan Qi ₁ , Ren Zhou ₁ , Chuanhai Guo ₁ , Anxiang Liu ₂ , Haijun Yang ₃ , Fenglei Li ₄ , Liping Duan ₅ , Lin Shen ₆ , Qi Wu ₇ , Zhen Liu ₁ , Yaqi Pan ₁ , Ying Liu ₁ , Fangfang Liu ₁ , Hong Cai ₁ , Zhonghu He ₈ , Yang Ke ₈

Affiliation

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Genetics, Peking University Cancer Hospital & Institute, Beijing, China.
Endoscopy Center, Anyang Cancer Hospital, Anyang, Henan Province, China.
Department of Pathology, Anyang Cancer Hospital, Anyang, Henan Province, China.
Hua County People's Hospital, Hua County, Henan Province, China.
Department of Gastroenterology, Peking University Third Hospital, Beijing, China.
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Gastrointestinal Oncology, Peking University Cancer Hospital & Institute, Beijing, China.
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Endoscopy Center, Peking University Cancer Hospital & Institute, Beijing, China.
State Key Laboratory of Molecular Oncology, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Genetics, Peking University Cancer Hospital & Institute, Beijing, China.

The aim of this study was to investigate the persistence of Lugol-unstained lesions (LULs) in the esophagus detected by chromoendoscopy and explore their association with progression to malignancy.

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