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Chronic berylliosis disease: uncommon pulmonary granulomas beyond sarcoidosis
Thorax ( IF 9.0 ) Pub Date : 2024-11-01 , DOI: 10.1136/thorax-2024-221555
Ahmed Ehab 1, 2 , Axel T Kempa 2 , Liubov Yurkul 2 , Ahmad Shalabi 3
Affiliation  

A 47-year-old male presented with chronic cough, which has worsened over the last 5–6 months. Dyspnoea, fever and significant weight loss were denied. The patient had no history of smoking or vaping. The patient worked as an automotive technician in a car manufacturing plant specialised in aluminium-based vehicle bodies with frequent exposure to metallic fumes during polishing and welding of aluminium/beryllium alloy for more than 26 years. There was no history of asbestos exposure. Respiratory examination was normal with no skin lesions or palpable lymphadenopathy. CT chest revealed mediastinal and hilar lymphadenopathy along with diffuse parenchymal opacities, including irregular nodular shadows and bilateral lung masses with irregular borders in both lower lobes (figure 1). The radiological findings raised suspicion for a metastatic disorder. Other possible differential diagnosis includes healed or non-specific granulomas, active granulomatous infection such …

中文翻译:


慢性铍病:结节病后不常见的肺肉芽肿



一名 47 岁男性因慢性咳嗽就诊,在过去 5-6 个月中病情加重。否认呼吸困难、发热和体重明显减轻。患者没有吸烟或电子烟史。该患者在一家专门生产铝基车身的汽车制造厂担任汽车技术员,在铝/铍合金的抛光和焊接过程中经常接触金属烟雾超过 26 年。没有石棉暴露史。呼吸检查正常,无皮损或可触及淋巴结肿大。胸部 CT 显示纵隔和肺门淋巴结肿大以及弥漫性的实质混浊,包括不规则的结节阴影和双侧肺肿块,双肺下叶边界不规则(图 1)。放射学检查结果怀疑存在转移性疾病。其他可能的鉴别诊断包括已愈合或非特异性肉芽肿、活动性肉芽肿感染,例如 ...
更新日期:2024-10-16
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