Nature Reviews Neurology ( IF 28.2 ) Pub Date : 2024-08-06 , DOI: 10.1038/s41582-024-01009-y Lisa Kiani 1
Seropositivity towards rubella virus (RV) increases the risk of developing multiple sclerosis (MS), according to new research. The case–control, Swedish biobank study analysed seropositivity towards RV in vaccinated and unvaccinated individuals before the clinical onset of MS. The results showed that people with MS had higher seroreactivity to RV than people without MS. Moreover, RV seropositivity was associated with a higher risk of developing MS in unvaccinated individuals. The finding adds to growing evidence for viral triggers of MS beyond the Epstein–Barr virus.
中文翻译:
风疹病毒可能会增加多发性硬化症的风险
最新研究表明,风疹病毒 (RV) 血清阳性会增加患多发性硬化症 (MS) 的风险。瑞典生物库的病例对照研究分析了 MS 临床发病前接种疫苗和未接种疫苗的个体的 RV 血清阳性情况。结果表明,患有多发性硬化症的人比没有多发性硬化症的人对 RV 的血清反应性更高。此外,RV 血清阳性与未接种疫苗的个体患 MS 的较高风险相关。这一发现为除爱泼斯坦-巴尔病毒之外的多发性硬化症病毒触发因素提供了更多证据。