To analyze the distribution and factors associated with lack of knowledge about the human papillomavirus (HPV) vaccine among Brazilian adolescents.Cross‐sectional study using the 2019 National School Health Survey among 17,805 Brazilian students of public and private schools, aged 13–17 years. The outcome variable was “lack of knowledge about the HPV vaccine” and the explanatory variables were sociodemographic, behaviors, knowledge, and health conditions. Logistic regression model was used to calculate Odds Ratio (OR) and 95% confidence intervals (95%CI). Spatial analysis techniques were used to determine the formation of clusters in the federated units with similar proportions of adolescents who were unaware of the vaccine. The lack of knowledge about the HPV vaccine was reported by 45.54% of Brazilian students. There was a higher chance of lack of knowledge having had sexual intercourse (OR 1.43; 95% CI 1.20–1.70); attending public school (OR 1.72; 95%CI 1.47–2.02) and located in the Northeast Region (OR 1.35; 95%CI 1.08–1.69). The lower chance of lack of knowledge were female gender (OR 0.41; 95% CI 0.35–0.48), higher maternal education (OR 0.62; 95% CI 0.50–0.77) self‐rated health as Poor/very poor (OR 0.64; 95% CI 0.49–0.86) and receiving contraceptive counseling (OR 0.77; 95% CI 0.65–0.91). The proportion of lack of knowledge about the HPV vaccine was higher with the formation of High–High spatial clusters in the states of Maranhão, Piauí, and Pernambuco. Sociodemographic, health, and behavioral conditions and knowledge of students, as well as school characteristics, were associated with lack of knowledge about the HPV vaccine. A higher frequency of lack of knowledge about the HPV vaccine among adolescents was found in the states of the Northeastern Region.

中文翻译：

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巴西青少年缺乏对人乳头瘤病毒疫苗的了解：一项横断面研究


分析巴西青少年对人乳头瘤病毒 (HPV) 疫苗缺乏了解的分布情况和相关因素。利用 2019 年全国学校健康调查对 17,805 名巴西公立和私立学校学生（年龄为 13-17 岁）进行横断面研究。结果变量是“缺乏有关 HPV 疫苗的知识”，解释变量是社会人口统计、行为、知识和健康状况。使用逻辑回归模型计算优势比 (OR) 和 95% 置信区间 (95%CI)。使用空间分析技术来确定联邦单位中不知道疫苗的青少年比例相似的集群的形成。 45.54%的巴西学生表示对HPV疫苗缺乏了解。缺乏性交知识的可能性较高（OR 1.43；95% CI 1.20-1.70）；就读公立学校（OR 1.72；95%CI 1.47–2.02）并且位于东北地区（OR 1.35；95%CI 1.08–1.69）。缺乏知识的可能性较低的是女性（OR 0.41；95% CI 0.35–0.48）、较高的母亲教育程度（OR 0.62；95% CI 0.50–0.77）、自评健康状况为差/非常差（OR 0.64；95） % CI 0.49–0.86）并接受避孕咨询（OR 0.77；95% CI 0.65–0.91）。随着马拉尼昂州、皮奥伊州和伯南布哥州形成高-高空间集群，对 HPV 疫苗缺乏了解的比例更高。社会人口、健康、行为状况和学生知识以及学校特点与缺乏 HPV 疫苗知识有关。东北地区各州青少年对 HPV 疫苗缺乏了解的频率较高。