Environmental–genetic interactions in ageing and dementia across Latin America,Nature Reviews Neurology

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Environmental–genetic interactions in ageing and dementia across Latin America
Nature Reviews Neurology ( IF 28.2 ) Pub Date : 2024-07-12 , DOI: 10.1038/s41582-024-00998-0
Agustin Ibanez _{1,

2} , Andrea Slachevsky _{3,

4,

5,

6}

Affiliation

Current dementia research has developed complex models of environmental–genetic interactions to better address multimodal disease phenotypes. New evidence highlights a stronger effect of social determinants of health than ancestry effects specific to Latin America and the Caribbean, which opens new agendas to address the diversity of these interactions in ageing and dementia. A new study on dementia prevalence in Latin America has found a stronger effect of social determinants of health than ancestry effects specific to this region, highlighting the need for interventions involving lifestyle changes, healthcare access and education.

中文翻译：

拉丁美洲老龄化和痴呆症的环境-遗传相互作用

目前的痴呆研究已经开发了复杂的环境 - 遗传相互作用模型，以更好地解决多模式疾病表型。新的证据强调，健康的社会决定因素比拉丁美洲和加勒比地区特有的血统影响更强，这为解决老龄化和痴呆中这些相互作用的多样性开辟了新的议程。一项关于拉丁美洲痴呆患病率的新研究发现，健康的社会决定因素的影响比该地区特有的血统影响更强，这突出了涉及生活方式改变、医疗保健获取和教育的干预措施的必要性。

更新日期：2024-07-12

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