Monitoring Intraabdominal Pressure (IAP) is essential in critical care, as elevated IAP can lead to severe complications, including Abdominal Compartment Syndrome (ACS). Advances in technology, such as digital capsules, have opened new avenues for measuring IAP non-invasively. This study assesses the feasibility and effectiveness of using a capsular device for IAP measurement in an animal model. In our controlled experiment, we anesthetized pigs and simulated elevated IAP conditions by infusing CO2 into the peritoneal cavity. We compared IAP measurements obtained from three different methods: an intravesical catheter (IAPivp), a capsular device (IAPdot), and a direct peritoneal catheter (IAPdir). The data from these methods were analyzed to evaluate agreement and accuracy. The capsular sensor (IAPdot) provided continuous and accurate detection of IAP over 144 h, with a total of 53,065,487 measurement triplets recorded. The correlation coefficient (R²) between IAPdot and IAPdir was excellent at 0.9241, demonstrating high agreement. Similarly, IAPivp and IAPdir showed strong correlation with an R² of 0.9168. The use of capsular sensors for continuous and accurate assessment of IAP marks a significant advancement in the field of critical care monitoring. The high correlation between measurements from different locations and methods underscores the potential of capsular devices to transform clinical practices by providing reliable, non-invasive IAP monitoring.

中文翻译：

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连续腹内压测量的验证：在体内研究中使用胶囊装置的可行性和准确性评估


监测腹内压 (IAP) 在重症监护中至关重要，因为 IAP 升高可导致严重并发症，包括腹腔室综合征 (ACS)。数字胶囊等技术进步为非侵入性测量 IAP 开辟了新途径。本研究评估了在动物模型中使用胶囊装置进行 IAP 测量的可行性和有效性。在我们的对照实验中，我们麻醉猪并通过将 CO2 注入腹膜腔来模拟升高的 IAP 条件。我们比较了通过三种不同方法获得的 IAP 测量结果：膀胱内导管 (IAPivp)、囊状装置 (IAPdot) 和直接腹膜导管 (IAPdir)。对这些方法的数据进行分析以评估一致性和准确性。囊状传感器 (IAPdot) 在 144 小时内连续准确地检测 IAP，总共记录了 53,065,487 个测量三联体。 IAPdot 和 IAPdir 之间的相关系数 (R²) 高达 0.9241，表现出高度一致性。同样，IAPivp 和 IAPdir 显示出很强的相关性，R² 为 0.9168。使用胶囊传感器对 IAP 进行连续、准确的评估标志着重症监护领域的重大进步。不同地点和方法的测量值之间的高度相关性强调了胶囊装置通过提供可靠、非侵入性 IAP 监测来改变临床实践的潜力。