BackgroundInhalant allergens provide a source of environmental factors that contribute to the development of clinical symptoms in patients with atopic dermatitis (AD).ObjectiveTo review the relationship between inhalant allergens and AD.MethodsA literature review was conducted using three databases: PubMed/MEDLINE, ClinicalKey, and Web of Science. Search terms, including “atopic dermatitis,” “atopic eczema,” and “eczema,” were used in combination with “inhalant allergen,” “inhaled allergen,” and “aeroallergen” to identify relevant published manuscripts that highlight the relationship between AD and exposures to inhalant allergens.ResultsFifteen articles were suitable for review. The studies included in the review investigated the effect of inhalant allergens on the clinical manifestations of AD through bronchial provocation, direct skin contact, and allergen sensitization.ConclusionThere is a significant relationship between exposures to inhalant allergens and AD. Inhalant allergens may aggravate AD symptoms by either bronchial provocation or direct skin contact. Sensitization of inhalant allergens, mainly house dust mites, follows a specific age-related pattern.

中文翻译：

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吸入性过敏原对特应性皮炎临床表现的作用


背景吸入性过敏原提供了导致特应性皮炎（AD）患者临床症状发生的环境因素来源。目的回顾吸入性过敏原与AD之间的关系。方法使用三个数据库进行文献综述：PubMed/MEDLINE、ClinicalKey、和科学网。搜索术语，包括“特应性皮炎”、“特应性湿疹”和“湿疹”，与“吸入性过敏原”、“吸入性过敏原”和“气源性过敏原”结合使用，以识别相关已发表的手稿，这些手稿强调了 AD 和暴露于吸入性过敏原。结果 15 篇文章适合审查。纳入综述的研究通过支气管激发、直接皮肤接触和过敏原致敏研究了吸入性过敏原对AD临床表现的影响。结论吸入性过敏原暴露与AD之间存在显着关系。吸入性过敏原可能会通过支气管刺激或直接皮肤接触而加重 AD 症状。吸入性过敏原（主要是屋尘螨）的致敏遵循特定的与年龄相关的模式。