Tetrahedron ( IF 2.1 ) Pub Date : 2023-12-29 , DOI: 10.1016/j.tet.2023.133816 Zhen Ding , Maodong Xu , Jiaxin Xie , Yilin Zhang , Xiaohan Lu , Siyu Lu , Tingxian Tao , Zhichuan Wu
Polyacrylonitrile (PAN) fibers were modified by hydroxylamine to obtain amidoxime fibers (AOFs) as the carrier, which was coordinated with PdCl2 solution to prepare amidoxime fibers supported Pd(II) [AOFs-Pd(II)] catalyst. A continuous flow reaction device was established to explore the coupling reaction of bromopyridine with styrene catalyzed by AOFs-Pd(II). The optimization was carried out to obtain the optimal process conditions, including temperature, flow rate, substrate concentration, catalyst stability, substrate applicability. The kinetic equations under continuous flow were obtained by fitting the data from the experiments using Matlab, and the reaction was determined to be a first-order reaction. Using the Arrhenius equation, the activation energy (Ea) was determined to be 7.65 kJ/mol.
中文翻译:
偕胺肟纤维负载钯催化溴吡啶与苯乙烯连续流偶联反应
采用羟胺对聚丙烯腈( PAN )纤维进行改性,得到偕胺肟纤维(AOFs)作为载体,与PdCl 2溶液配位制备偕胺肟纤维负载Pd(II)[AOFs-Pd(II)]催化剂。搭建连续流反应装置,探索AOFs-Pd(II)催化溴吡啶与苯乙烯的偶联反应。进行优化以获得最佳工艺条件,包括温度、流量、底物浓度、催化剂稳定性、底物适用性。利用Matlab对实验数据进行拟合,得到连续流下的动力学方程,确定该反应为一级反应。使用阿伦尼乌斯方程,确定活化能 ( E a ) 为 7.65 kJ/mol。