<br>育空地区北部传统食品中六氯苯和 omega-3 脂肪酸的摄入量：风险与效益分析,Science of the Total Environment

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育空地区北部传统食品中六氯苯和 omega-3 脂肪酸的摄入量：风险与效益分析
Science of the Total Environment ( IF 8.2 ) Pub Date : 2023-12-23 , DOI: 10.1016/j.scitotenv.2023.169205
Mallory Drysdale ₁ , Mary Gamberg ₂ , Jeremy Brammer ₃ , Shannon E Majowicz ₁ , Sara Packull-McCormick ₁ , Kelly Skinner ₁ , Brian D Laird ₁

Affiliation

2019 年，在育空地区 Old Crow 社区进行了一项人体生物监测研究，发现该社区血浆中的六氯苯 (HCB) 水平相对于加拿大普通人群有所升高。本研究的目的是估算 Old Crow 当地收获的传统食物中六氯苯和营养 omega-3 脂肪酸的膳食摄入量，旨在确定可能的区域暴露源。构建了随机模型来估计六氯苯和 omega-3 脂肪酸二十碳五烯酸 (EPA) 和二十二碳六烯酸 (DHA) 的摄入量。 Old Crow 传统食物消费的平均预测六氯苯暴露水平均低于 1600-1700 ng/kg 体重/天的每日耐受摄入量，无论是平均摄入量（18 ng/kg 体重/天）还是短期最大摄入量（27 ng/kg 体重/天）。 /kg体重/天）暴露模型。平均六氯苯摄入量的主要贡献者是驯鹿脂肪、骨髓、肋骨、肾脏以及奇努克鲑鱼肌肉。在平均（1.6 克/周）暴露模型中，来自传统食品的平均估计膳食 EPA + DHA 摄入量低于建议的每周 2.1 至 3.2 克 EPA + DHA，但高于短期最大模型中的建议（ 3.3 克/周）。平均 EPA + DHA 摄入量的主要贡献者是奇努克鱼、银鲑鱼和大马哈鱼的肌肉、白鲑的肌肉和鱼卵。这项研究的结果支持了这样的信息：传统食品仍然是营养和其他健康益处的重要来源，并且传统食品的健康益处通常超过污染物风险。

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Hexachlorobenzene and omega-3 fatty acid intake from traditional foods in the northern Yukon: A risk and benefit analysis

A human biomonitoring study was conducted in the community of Old Crow, Yukon, in 2019, finding that levels of hexachlorobenzene (HCB) in plasma were elevated in the community relative to the general Canadian population. The aim of this study was to estimate dietary intake of both hexachlorobenzene, and the nutrient omega-3 fatty acids from locally harvested traditional foods in Old Crow, with the aim of identifying possible regional sources of exposure. A stochastic model was constructed to estimate intake of both hexachlorobenzene and the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Average predicted hexachlorobenzene exposure levels from traditional food consumption in Old Crow were below the tolerable daily intake of 1600–1700 ng/kg body weight/day in both average (18 ng/kg body weight/day) and short-term maximum (27 ng/kg body weight/day) exposure models. The primary contributors to average hexachlorobenzene intake were caribou fat, bone marrow, ribs, and kidneys, and Chinook salmon muscle. Average estimated dietary EPA + DHA intake levels from traditional foods were below the recommendation of 2.1 to 3.2 g of EPA + DHA per week in the average (1.6 g/week) exposure model, but above this recommendation in the short-term maximum model (3.3 g/week). The primary contributors to average EPA + DHA intake were the meat of Chinook, coho, and, chum salmon muscle, and whitefish muscle and eggs. The results of this study support the message that traditional foods continue to be an important source of nutrients and other health benefits and that the health benefits of traditional foods generally outweigh contaminant risks.

更新日期：2023-12-23

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